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Titlebook: Drugs Affecting Lipid Metabolism; A. L. Catapano,A. M. Gotto (Chairman),Rodolfo Paol Book 1993 Springer Science+Business Media Dordrecht 1

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書目名稱Drugs Affecting Lipid Metabolism
編輯A. L. Catapano,A. M. Gotto (Chairman),Rodolfo Paol
視頻videohttp://file.papertrans.cn/284/283177/283177.mp4
叢書名稱Medical Science Symposia Series
圖書封面Titlebook: Drugs Affecting Lipid Metabolism;  A. L. Catapano,A. M. Gotto (Chairman),Rodolfo Paol Book 1993 Springer Science+Business Media Dordrecht 1
描述A great deal of experimental, clinical and epidemiological datahave been gathered to confirm the strict and causal correlationbetween plasma lipoproteins and coronary heart disease. However, asusually happens in research, many more interesting issues are beingstudied, opening new fields of research for the future. These newadvances, together with the combined efforts of cell biologists andlipoprotein chemists, have set the pace for an exciting period ofresearch and clinical applications of diets and drugs affecting plasmaand cell lipids. This volume, which includes the work of many of theleading world labortories, represents an authoritative and up-to-dateappraisal of the status of the art and a stimulus to future researchat the laboratory and clinical level in a fascinating area of clinicaland preventive medicine..
出版日期Book 1993
關(guān)鍵詞Lipoprotein; atherosclerosis; heart; lipide; metabolism; research; thrombosis
版次1
doihttps://doi.org/10.1007/978-94-011-1703-6
isbn_softcover978-94-010-4746-3
isbn_ebook978-94-011-1703-6Series ISSN 0928-9550
issn_series 0928-9550
copyrightSpringer Science+Business Media Dordrecht 1993
The information of publication is updating

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Influence of Atherogenic Lipoproteins on The Thrombotic Potential of Endothelial Cells,ata in the literature indicate that LDL as well as modified LDL influence a variety of functional aspects of endothelial cells, that include adhesive properties for monocytes/macrophages and regulation of vascular tone. In addition these lipoproteins influence the capacity of endothelial cells both
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Three Liver-Enriched Transcription Factors: HNF-1, C/EBP, and Protein II are Required to Enhance Tr is found in B 443 base pair (bp) fragment (+621 to +1064) that is located entirely within the second intron of the gene. Within this fragment, a 147-bp region (+806 to +952) containing a single 97-bp DNasel footprint exhibits significant enhancer activity. We now report that this footprint contains
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Structure-Function Relationships of Apolipoprotein B-100,es, such as investigations in cultured cells, and in human subjects with specific apoB mutations also have their limitations a novel approach using transgenic mice has yielded interesting information on the low density lipoprotein-associating function of apoB-100. In future, transgenic animals expre
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Contribution of Helix-Helix Interactions to the Stability of Apolipoprotein-Lipid Complexes,zed. In discoidal lipid-apoprotein complexes, these helixes are oriented parallel to the phospholipid acyl chains around the edge of the disc, and antiparallel to each other. The residues on the side of the contiguous helixes are in close vicinity and can form salt bridges. Computer modeling of apo
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Lipoprotein Assembly: A Potential Target for Drugs Affecting Lipid Metabolism,h the liver and intestine. The gene responsible for this disease does not co-segregate with the apo a gene suggesting it is caused by the loss of some gene product. To gain an understanding of the apparently unique process necessary for apo a secretion, plasmids expressing apo a were transfected int
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