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Titlebook: Drug Toxicity in Embryonic Development I; Advances in Understa Robert J. Kavlock (Director),George P. Daston Book 1997 Springer-Verlag Berl

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發(fā)表于 2025-3-21 16:34:13 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Drug Toxicity in Embryonic Development I
副標(biāo)題Advances in Understa
編輯Robert J. Kavlock (Director),George P. Daston
視頻videohttp://file.papertrans.cn/284/283139/283139.mp4
叢書名稱Handbook of Experimental Pharmacology
圖書封面Titlebook: Drug Toxicity in Embryonic Development I; Advances in Understa Robert J. Kavlock (Director),George P. Daston Book 1997 Springer-Verlag Berl
描述Having received the invitation from Springer-Verlag to produce a volume on drug-induced birth defects for the Handbook of Experimental Pharmacology, we asked ourselves what new approach could we offer that would capture the state of the science and bring a new synthesis of the information on this topic to the world‘s literature. We chose a three-pronged approach, centered around those particular drugs for which we have a relatively well established basis for understanding how they exert their unwanted effects on the human embryo. We then supplemented this information with a series of reviews of critical biological processes involved in the established normal developmental patterns, with emphasis on what happens to the embryo when the processes are perturbed by experimental means. Knowing that the search for mechanisms in teratology has often been inhibited by the lack of understanding of how normal development proceeds, we also included chapters describing the amazing new discoveries related to the molecular control of normal morphogenesis for several organ systems in the hope that the experimental toxicologists and molecular biologists will begin to better appreciate each others q
出版日期Book 1997
關(guān)鍵詞Geburtsschaden; Morphogenese; abnormal development; birth; birth defects; drug; drugs; embryo; morphogenesis
版次1
doihttps://doi.org/10.1007/978-3-642-60445-4
isbn_softcover978-3-642-64408-5
isbn_ebook978-3-642-60445-4Series ISSN 0171-2004 Series E-ISSN 1865-0325
issn_series 0171-2004
copyrightSpringer-Verlag Berlin Heidelberg 1997
The information of publication is updating

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Introduction: 1918–28, Contexts and Textsinct from cleft lip (CL) with or without cleft palate, which has a frequency of 8 per 10 000 live births (B. et al. 1994). A number of reviews have been written on palate development (Z. 1984; P. and G. 1986; F. 1988).
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Introduction: 1918–28, Contexts and Textsd Harold Kalter. Also at that time, the University of Cincinnati was one of only a very few institutions that actually granted a Ph.D. degree in “Developmental Biology.” This interdisciplinary degree was based firmly on the study of abnormal development as a window into the regulation of normal embryogenesis.
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https://doi.org/10.1007/978-1-349-19362-2ted in Fig. 1. Each prostaglandin is designated by a letter of the alphabet, A–J, according to the composition of its cyclopentane ring, and by a numerical subscript indicating the number of double bonds in the alkyl side chains. In prostaglandins of the F series, subscripts α or β indicate the orientation of the hydroxyl group at C-9 in the ring.
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Class and Gender: The ‘Girls’ Weeklies’ic development, reduction of superfluous cells, disposal of cells that have already completed their functions, elimination of cells which differentiate inappropriately, and suppression of potentially harmful or abnormal cells (S. 1966; E. et al 1991).
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