Titlebook: Drug Discovery and Evaluation: Methods in Clinical Pharmacology; Franz J. Hock,Michael R. Gralinski Reference work 2020Latest edition Spri

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Reference work 2020Latest editionhird volume: ?Methods in Clinical Pharmacology"...For the 2nd?edition of this volume, the chapters have been revised and completely updated. A large number of assays were added. New chapters were included, such as pain, addiction, gene therapy, orphan diseases..

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Pharmacodynamic Evaluation: Ocular Pharmacologyhe optic nerve that connects the retina to the brain. Many decades of basic and applied research have resulted in the discovery and development of different types of pharmacological agents (small molecules), peptides, and antibodies that help clinically manage the various ocular disorders mentioned

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Clinical Aspects in Sleep Disorders and Apneaior, activity, and physiological signals; and finally a sleep laboratory investigation, cardiorespiratory polysomnography, with all signals recorded which change during normal and pathological sleep. Quantitative assessment of sleep, sleep stages, arousals from sleep, and vegetative functions during

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Pharmacodynamic Evaluation: Infectious Diseases citing their advantages and limitations, along with simulations for optimizing treatment regimens. Furthermore, it describes the applications of pharmacodynamic models for treatment of bacterial infections and, finally, the pathophysiological conditions leading to treatment failures and strategies