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Titlebook: Drug Discovery; A Casebook and Analy Robert A. Maxwell,Shohreh B. Eckhardt Book 1990 Springer Science+Business Media New York 1990 calcium.

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書目名稱Drug Discovery
副標(biāo)題A Casebook and Analy
編輯Robert A. Maxwell,Shohreh B. Eckhardt
視頻videohttp://file.papertrans.cn/284/283065/283065.mp4
圖書封面Titlebook: Drug Discovery; A Casebook and Analy Robert A. Maxwell,Shohreh B. Eckhardt Book 1990 Springer Science+Business Media New York 1990 calcium.
描述This treatise had its origins in the authors‘ strong opinion that the discovery of new drugs, especially of innovative therapeutic agents, really does not happen as a spontaneous sequel to investiga- tive research, no matter how penetrating such research may be. Rather, it seemed to us that the discovery of innovative therapeutic agents was a very active process, existing in and of itself, and demanding full attention-it was not simply a passive, dependent by-process of investigative research. And yet, many researchers- some close confreres of the authors, others more distant-believed otherwise. We felt that their view reflected unrealistic thinking and that reality probably lay closer to what Beyer" maintained: We are taught to believe that if we can understand a disease it should be easy enough to figure out, say, the molecular configuration of a definitive receptor mechanism somewhere along the line and to design a specific drug . . . . And so we start out to understand the disease but never get around to doing much about therapy. The authors very soon realized that there was essentially no quantitive information available on just where and how innovative therapeutic agents were
出版日期Book 1990
關(guān)鍵詞calcium; clinical research; drug; drug discovery; research; transplantation
版次1
doihttps://doi.org/10.1007/978-1-4612-0469-5
isbn_softcover978-1-4612-6775-1
isbn_ebook978-1-4612-0469-5
copyrightSpringer Science+Business Media New York 1990
The information of publication is updating

書目名稱Drug Discovery影響因子(影響力)




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書目名稱Drug Discovery網(wǎng)絡(luò)公開度學(xué)科排名




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Furosemide The former appellation refers loosely to the site of action of these agents within the nephron—the loop of Henle—and the latter to the fact that the maximum diuresis achieved with these drugs far exceeded that obtained with the thiazide diuretics.
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Cyclosporineioprine in 1959 and its subsequent combination with steroids established kidney transplantation as a viable therapy for renal failure. However, although this regimen represented a major step forward, only 50% of the allografts (homografts) achieved with it were functional, and these were accompanied
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Chlorpromazineld. Until the early 1950s it was treated with electroconvulsive shock or hypoglycemie shock induced with insulin, often resulting in memory dysfunction, amnesia, and subtle impairment of cognitive function (Taylor, 1982; Squire, 1982). In addition, drugs (barbiturates, morphine, and other sedatives)
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Imipramines, it was called melancholia. It comprises two major types: (1) severe depression of mood associated with psychomotor retardation or agitation, self-reproach or guilt, as well as other symptoms, all of which occur in the apparent absence of a precipitating cause; (2) severe depression of mood associ
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