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Titlebook: Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases; Christopher L. Cioffi Book 2020 Springer Nature Switzerlan

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發(fā)表于 2025-3-21 17:52:28 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書(shū)目名稱Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases
編輯Christopher L. Cioffi
視頻videohttp://file.papertrans.cn/284/283037/283037.mp4
概述Presents the current state of ocular drug therapy.Reviews the unique challenges faced for ocular drug discovery and delivery.Highlights future therapeutic opportunities for age-related macular degener
叢書(shū)名稱Topics in Medicinal Chemistry
圖書(shū)封面Titlebook: Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases; Christopher L. Cioffi Book 2020 Springer Nature Switzerlan
描述.This book reviews the current state of ocular drug therapy and future therapeutic opportunities for a wide variety of conditions, including Age-related Macular Degeneration, Diabetic Retinopathy and Macular Edema, Glaucoma, and Inherited Retinal Diseases..Retinal diseases are major contributors to moderate or severe vision impairment in adults aged 50 years and older. The respective patient populations for many of these indications is expected to significantly increase as the world population continues to grow older. An improved understanding of the etiological underpinnings of ocular degenerative diseases over the past decade has significantly bolstered ophthalmic drug discovery..In this volume, contributions from leading experts explore the unique challenges faced for ocular drug discovery and delivery providing the reader with detailed information on ocular pharmacokinetics, .in vitro, ex vivo. and .in vivo. models for retinal disease pathology and emerginggene therapy treatments. The book is intended for all researchers and clinicians who wish to increase their knowledge on the latest findings in ocular drug therapy..
出版日期Book 2020
關(guān)鍵詞Macular Degeneration; Stargardt Disease; Glaucoma; Diabetic Retinopathy; Diabetic Macular Edema; Ocular P
版次1
doihttps://doi.org/10.1007/978-3-030-56619-7
isbn_softcover978-3-030-56621-0
isbn_ebook978-3-030-56619-7Series ISSN 1862-2461 Series E-ISSN 1862-247X
issn_series 1862-2461
copyrightSpringer Nature Switzerland AG 2020
The information of publication is updating

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978-3-030-56621-0Springer Nature Switzerland AG 2020
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https://doi.org/10.1007/978-3-662-36243-3o major clinical presentations of AMD: atrophic or “dry” and neovascular or “wet.” Geographic atrophy (GA) is the most severe manifestation of dry AMD which represents the form of the disease characterized by the highest prevalence. A smaller fraction of AMD patients (10–20%) develop choroidal neova
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https://doi.org/10.1007/978-3-662-36243-3but the number of clinical gene therapy trials has been very limited. The improved visual function outcomes in individuals affected by retinal dystrophy caused by biallelic variants in the RPE65 gene after gene therapy treatment contributed to the US Food and Drug Administration (FDA) and European M
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