Titlebook: Drug Delivery; Materials Design and Eric P. Holowka,Sujata K. Bhatia Textbook 2014 Springer Science+Business Media New York 2014 Controlled

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Smart Drug Delivery Systems,sented a simple, idealized, gradual release response, which allowed for a predicted dosage to be delivered over a predictable time regime. As we shifted our discussion to encapsulated and targeted systems, it became apparent that the zero-order release would be less relevant since the design strateg

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Conclusion,dvances in multiple fields, including polymer science, molecular biology, nanotechnology, and chemical engineering. Novel structures for drug delivery incorporate hydrogels, micelles, liposomes, and thin films with unique mechanical and biological properties. These structures can be designed for res

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Textbook 2014nowledge using prominent examples from both the scientific literature and clinical practice. Each chapter focuses on a specific drug delivery technology, such as controlled-release materials, thin-film materials, or smart materials. Within each chapter, an initial section on “Engineering Concepts” r

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https://doi.org/10.1007/978-3-662-29503-8. At the root, the drug designer tries to address as many of these confounding properties as possible, searching for an effective chemical structure capable of treatment within an acceptable dosage window, but still there are compromises. With each new drug introduced into the pharmaceutical market,

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https://doi.org/10.1007/978-3-662-29503-8tistically likely to hit a bull’s-eye, but you are also more likely to damage the wall as well! A controlled-release profile can allow for targeting of the delivery, improve the availability of the drugs (i.e., short half-lives), and can serve multiple functions within the system (i.e., release syst