Titlebook: Drug Allergy; Clinical Aspects, Di Brian A. Baldo,Nghia H. Pham Book 2021Latest edition Springer Nature Switzerland AG 2021 drug allergies.

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Contrast Media,oms, and non-ionic agents are tolerated better than ionics. Reactions can be immediate (IR) or delayed (DR). Incidences of the former are 3–4% (ionics), 0.2–0.7% (non-ionics), severe reactions 0.1–0.4% (ionics), and 0.02–0.04% (non-ionics). Up to 80% of reactions can be avoided by using non-ionic ag

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Corticosteroids,rgic reactions. Frequency of reactions after topical application is 0.2–5.98%; for systemic reactions, the incidence is 0.1–0.3%. The reaction of steroid glyoxals with arginine is important for allergenicity of CSs. Allergic contact eczema is the most common delayed hypersensitivity reaction to CSs.

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Targeted Drugs for Cancer Therapy: Small Molecules and Monoclonal Antibodies,erapy. Effective targeting of tumor cells without accompanying toxicity has started to be realized with the introduction of signal transduction therapies and monoclonal antibodies (mAbs). Small molecule examples of the former drugs include imatinib (which inhibits both the ABL and BCR-ABL tyrosine k

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Vaccines, attenuated vaccines are generally more potent than killed vaccines, but a potential disadvantage of live vaccines is the possibility of a lethal systemic infection in immunosuppressed or immunoglobulin-deficient individuals. To overcome some of the problems and risks of live vaccines, subunit vacci

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