Titlebook: Dopaminergic Systems and their Regulation; G. N. Woodruff (Director of Pharmacology),J. A. Po Book 1986 The Contributors 1986 dopamine.reg

殺死

Conclusive Evidence for Two Subtypes of Peripheral Dopamine Receptorsteristics of putative DA receptors identified in other areas (Goldberg, 1978). At that time we had studied more than 200 close structural analogs of DA and found that only a few compounds were active as DA agonists. Most of our studies were conducted in the canine renal vascular bed pretreated with

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Dynamic Changes in Brain Dopamine Metabolism During Movementter turnover in brain. The goal was to study normal brain function without the need for drugs or lesions. We have trained rats to run in circles for a water reward and have also studied animals running at different speeds on straight and circular treadmills. The purpose of these assigned motor tasks

發(fā)源

Neuropeptide-Dopamine Interactions: Focus on Neurotensinopamine in the central nervous system (CNS). Accumulating evidence supports the contention that these interactions are of physiological importance and have added a novel dimension to our concepts of the pathophysiology of psychiatric disorders and the mechanisms of psychotropic drug action. Primary

endure

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Dopamine Release and Metabolism in Awake Rats after Systemic Neuroleptics as Studied by Brain Dialyslipson and Horn, 1976; Spano et al., 1976; Spano et al., 1977) or on the DA-neurons themselves, either in the caudate (terminal auto-receptors) (Carlsson, 1975), or in the nigra (nigral auto-receptors) (Aghajanian and Bunney, 1977).

deriver

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厭惡

DARPP-32: A Dopamine-regulated Phosphoprotein in the Basal Ganglialocal application or systemic administration of dopamine agonists generates behaviors or physiological responses which can be blocked by specific dopamine antagonists (e.g. Ungerstedt, 1979; Costall and Naylor, 1979; Iversen and Iversen, 1981).