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Titlebook: Dissecting Regulatory Interactions of RNA and Protein; Combining Computatio Marvin Jens Book 2014 Springer International Publishing Switzer

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發(fā)表于 2025-3-21 17:22:20 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Dissecting Regulatory Interactions of RNA and Protein
副標(biāo)題Combining Computatio
編輯Marvin Jens
視頻videohttp://file.papertrans.cn/282/281614/281614.mp4
概述Nominated as an outstanding PhD thesis by Max Delbrueck Center for Molecular Medicine, Germany.Combines concepts and approaches from physics with high-throughput data to model gene regulation and answ
叢書名稱Springer Theses
圖書封面Titlebook: Dissecting Regulatory Interactions of RNA and Protein; Combining Computatio Marvin Jens Book 2014 Springer International Publishing Switzer
描述.The work described in this book is an excellent example of interdisciplinary research in systems biology. It shows how concepts and approaches from the field of physics can be efficiently used to answer biological questions and reports on a novel methodology involving creative computer-based analyses of high-throughput biological data. Many of the findings described in the book, which are the result of collaborations between the author (a theoretical scientist) and experimental biologists and between different laboratories, have been published in high-quality peer-reviewed journals such as Molecular Cell and Nature. However, while those publications address different aspects of post-transcriptional gene regulation, this book provides readers with a complete, coherent and logical view of the research project as a whole. The introduction presents post-transcriptional gene regulation from a distinct angle, highlighting aspects of information theory and evolution and laying the groundwork for the questions addressed in the subsequent chapters, which concern the regulation of the transcriptome as the primary functional carrier of active genetic information..
出版日期Book 2014
關(guān)鍵詞Binding site occupancy; CDR1as; Competing RNA; ELAVL1 HuR; Model of ELAVL1 binding; PAR-CLIP clusters and
版次1
doihttps://doi.org/10.1007/978-3-319-07082-7
isbn_softcover978-3-319-36117-8
isbn_ebook978-3-319-07082-7Series ISSN 2190-5053 Series E-ISSN 2190-5061
issn_series 2190-5053
copyrightSpringer International Publishing Switzerland 2014
The information of publication is updating

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The Complete Handbook of the Internetonal analysis and filtering of the resulting sequencing data are explained. The design and function of the computational PAR-CLIP analysis pipeline used in the Rajewsky lab is presented, with a special emphasis on controlling false-positive read mapping errors.
地板
發(fā)表于 2025-3-22 06:58:37 | 只看該作者
David R. Anderson MD,John G. Kelton MDnstants of regulation,” which emerge from the composition of the transcriptome as a whole is put forward, based on the idea that the function of transcriptome regulators depends on the complete pool of RNA. This implies higher levels of homeostatic control and motivates future studies.
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發(fā)表于 2025-3-22 11:43:53 | 只看該作者
Book 2014he field of physics can be efficiently used to answer biological questions and reports on a novel methodology involving creative computer-based analyses of high-throughput biological data. Many of the findings described in the book, which are the result of collaborations between the author (a theore
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發(fā)表于 2025-3-22 16:00:09 | 只看該作者
Introduction,low functional, specific regulatory control by an RBP or regulatory RNA are explored from the perspective of the regulator, with statistics on the composition of the cellular RNA pool (the transcriptome).
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發(fā)表于 2025-3-22 20:16:15 | 只看該作者
Computational Analysis of PAR-CLIP Data,onal analysis and filtering of the resulting sequencing data are explained. The design and function of the computational PAR-CLIP analysis pipeline used in the Rajewsky lab is presented, with a special emphasis on controlling false-positive read mapping errors.
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