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Titlebook: Disordered Vertebral and Rib Morphology in Pudgy Mice; Structural Relations Frederic Shapiro Book 2016 The Editor(s) (if applicable) and Th

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發(fā)表于 2025-3-21 18:51:36 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Disordered Vertebral and Rib Morphology in Pudgy Mice
副標(biāo)題Structural Relations
編輯Frederic Shapiro
視頻videohttp://file.papertrans.cn/282/281476/281476.mp4
概述Provides information on a structural study on vertebral abnormalities.Casts new light on human congenital scoliosis and spondylocostal dysplasia.Deals with all aspects of embryo and neonatal developme
叢書名稱Advances in Anatomy, Embryology and Cell Biology
圖書封面Titlebook: Disordered Vertebral and Rib Morphology in Pudgy Mice; Structural Relations Frederic Shapiro Book 2016 The Editor(s) (if applicable) and Th
描述?This book presents results obtained from the whole mount preparations, radiological, and histological studies of 60 pu/pu and pu/+ mice from late embryo until 3 months of age. Most mice were in the embryo to 6 week age group where vertebral developmental changes are most marked. Although vertebral abnormalities have been identified as due to mutations in the delta-like 3 (Dll3) gene, it is evident that each mouse has differing structural abnormalities. The disorder is analogous to human congenital scoliosis, a common variant of which is spondylocostal dysplasia. The histological studies presented in this book include plastic embedded sections?which?allow for high level resolution not only of?vertebrae, intervertebral discs, and ribs but also of associated spinal cord, nerve roots and ganglia. In addition an overview of embryo and neonatal development in mouse, chick and human vertebrae is provided to better assess how and where deviant pathoanatomy occurs. The book discusses the possible variables involved in creating final deformity beyond the gene abnormality itself.
出版日期Book 2016
關(guān)鍵詞congenital scoliosis; human vertebral development; morphological gradients in deformity; spondylocostal
版次1
doihttps://doi.org/10.1007/978-3-319-43151-2
isbn_softcover978-3-319-43149-9
isbn_ebook978-3-319-43151-2Series ISSN 0301-5556 Series E-ISSN 2192-7065
issn_series 0301-5556
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl
The information of publication is updating

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沙發(fā)
發(fā)表于 2025-3-21 22:13:06 | 只看該作者
板凳
發(fā)表于 2025-3-22 03:48:50 | 只看該作者
Discussion,, intervertebral disc, and rib abnormalities in the development of the pudgy mouse. The end result demonstrates a failure of both normal formation and normal segmentation in the pudgy mouse recognized now as a recessive genetic disorder in which mutations in the . have been defined [2]. The variable
地板
發(fā)表于 2025-3-22 07:07:51 | 只看該作者
Conclusions,costal dysplasias. The pudgy mouse is an excellent model to study: (i) how gene mutations translate into three-dimensional structural abnormalities and (ii) which other factors contribute to the final deformities.
5#
發(fā)表于 2025-3-22 09:37:33 | 只看該作者
6#
發(fā)表于 2025-3-22 15:49:45 | 只看該作者
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發(fā)表于 2025-3-22 18:02:12 | 只看該作者
Robot Installation in Telemicrosurgerygous unaffected littermates served as controls. An affected pudgy mouse (pu/pu) can be identified at birth since it is approximately three-quarters the length of its non-affected littermates (pu/+) and has a markedly shortened, twisted tail. The mice were sacrificed by intraperitoneal injections of
8#
發(fā)表于 2025-3-23 00:27:27 | 只看該作者
Jonathan A. Segal,Janet B. Allen, intervertebral disc, and rib abnormalities in the development of the pudgy mouse. The end result demonstrates a failure of both normal formation and normal segmentation in the pudgy mouse recognized now as a recessive genetic disorder in which mutations in the . have been defined [2]. The variable
9#
發(fā)表于 2025-3-23 03:28:05 | 只看該作者
Christiane Heckel,Kathrin Wiesecostal dysplasias. The pudgy mouse is an excellent model to study: (i) how gene mutations translate into three-dimensional structural abnormalities and (ii) which other factors contribute to the final deformities.
10#
發(fā)表于 2025-3-23 09:28:25 | 只看該作者
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