Titlebook: Diagnostic and Therapeutic Advances in Pediatric Oncology; David O. Walterhouse,Susan L. Cohn Book 1997 Springer Science+Business Media Ne

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Immunodeficiency states and related malignanciesof the problem drew the interest of experts in lymphoma morphology, it became clear that these were primarily B-lymphoid lymphoproliferations that ranged from benign, but aggressive, to frankly malignant diseases. Some of this understanding came as the result of improved classifications of lymphomas

Blazon

infarct

Molecular basis of Wilms’ tumorumors. The generally favorable outcome for Wilms’ tumor patients can be partly attributed to medical advances, including refinement in surgical technique, the sensitivity of Wilms’ tumor to irradiation, and the availability of several active chemotherapeutic agents. The successful application of the

Baffle

Neuroblastoma: solving a biologic puzzle. While virtually all patients with localized neuroblastoma can be cured by surgery alone, and most infants with disseminated disease are curable with chemotherapy, children with bone metastases usually have a fatal outcome [1–4]. Furthermore, in some patients the tumor undergoes spontaneous regress

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Pediatric germ cell tumorsfferent degrees of malignancy and arising at different sites of origin. Only in the last decade has the biologic heterogeneity of germ cell tumors been recognized and addressed. Therapy tailored for the many biologically distinct subsets of germ cell tumors has yet to be defined. Because many catego

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Habituate

The Ewing’s sarcoma family of tumors: Ewing’s sarcoma and peripheral primitive neuroectodermal tumorese small round cell tumors of bone came to be known as .. Soft tissue variants are called . Ewing’s sarcoma [2, 3] and the Askin tumor [4]. Bone and soft tissue tumors, which are quite similar to Ewing’s sarcoma under the light microscope but which have notable neural differentiation, have been den

STALL

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Late effects of cancer therapy0% overall, with many subsets of patients demonstrating even worse outcome [1]. However, in the last three decades, treatment for malignancy in children has become far more effective. By the late 1980s, 60% to 70% of children with cancer (figure 1) were surviving their illness [2]. Although outcomes