Titlebook: Diagnosis and Management of Cholangiocarcinoma; A Multidisciplinary James H. Tabibian Book 2021 Springer Nature Switzerland AG 2021 biliar

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Anatomy of the Biliary Tree: Normal, Anomalous, and Relationship to Cholangiocarcinomaations on standard biliary anatomy can pose particular surgical challenges. This chapter will examine biliary anatomy, in particular its common variants and anomalies, with special attention to its relationship with cholangiocarcinoma and its treatment.

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Endoscopic Management of Cholangiocarcinomaapter we describe old and new endoscopic techniques with some perspectives regarding future developments in the field and the enduring need to help improve survival associated with this aggressive malignancy.

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The Role of Endoscopic Ultrasound in Cholangiocarcinoma EUS can be useful in providing enhanced staging data, primarily via improved nodal assessment. Although primary sclerosing cholangitis and the presence of biliary stents can hinder EUS performance, their impact is greatly minimized by adopting careful examination techniques.

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Intraductal Tumors of the Biliary Tract: Precursor Lesions and Variantsand genetic alterations. Cross-sectional imaging is valuable for delineation of bile duct dilatation and intraductal masses. Cholangiography and cholangioscopy are used to detect mucin hyperproduction, observe the tumor and biliary mucosa, and obtain tissue and cytology samples. Treatment should be

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Imaging of Cholangiocarcinomal polypoid); in general, it reflects the heterogeneous presentation of cholangiocarcinoma, with characteristic but nonspecific features that include a metabolically active mass with irregular, peripheral arterial hyperenhancement with gradual centripetal delayed enhancement, as well as biliary ducta

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Challenges in Diagnosing Cholangiocarcinoma: Pulling Together Biochemical, Radiological, and Cytopatologists, and pathologists. In some cases, despite a meticulous patient history, physical examination, and evaluation of imaging and laboratory tests by multidisciplinary experts, a diagnosis cannot be established with absolute certainty, and treatment may sometimes be started based on CCA being the

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Fluke-Associated Cholangiocarcinoma: A Regional Epidemics) and papillary carcinoma (accounting for the remaining third). The prognosis of CCA is dismal, with only half of patients surviving more than a year. Of note, the papillary phenotype of CCA has a better prognosis, which is attributable to the exophytic nature of the tumors, their late invasion int