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Titlebook: Diabetes, Insulin and Alzheimer‘s Disease; Suzanne Craft,Yves Christen Book 2010 Springer-Verlag Berlin Heidelberg 2010 Alzheimer.Alzheime

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發(fā)表于 2025-3-21 16:54:02 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Diabetes, Insulin and Alzheimer‘s Disease
編輯Suzanne Craft,Yves Christen
視頻videohttp://file.papertrans.cn/271/270452/270452.mp4
概述Includes supplementary material:
叢書名稱Research and Perspectives in Alzheimer‘s Disease
圖書封面Titlebook: Diabetes, Insulin and Alzheimer‘s Disease;  Suzanne Craft,Yves Christen Book 2010 Springer-Verlag Berlin Heidelberg 2010 Alzheimer.Alzheime
描述.Neurons share more similarities with insulin-producing pancreatic islet cells than with any other cell type. The root of this similarity may lie in the islet’s evolution from an ancestral insulin-producing neuron. The islet-neuron connection becomes less surprising as we learn more about insulin’s involvement in functions far from its traditional role in mediating glucose uptake in muscle. The importance of insulin in the regulation of corporal aging has been established by the dramatic increases in longevity experienced by animals in which the adipose insulin receptor has been genetically eliminated, or in which the insulin-related daf genes have been mutated. New research suggests that, analogous to its influence on corporal aging, insulin also makes important contributions to brain aging and the expression of late-life neurodegenerative disease. Insulin plays a key role in cognition and other aspects of normal brain function. Insulin resistance induces chronic peripheral insulin elevations and is associated with reduced insulin activity both in periphery and brain. The insulin resistance syndrome underlies conditions such as Type 2 diabetes mellitus and hypertension, which are
出版日期Book 2010
關(guān)鍵詞Alzheimer; Alzheimer′s disease; Diabetes; Insulin; aging; brain-insulin connection; growth factor; insulin
版次1
doihttps://doi.org/10.1007/978-3-642-04300-0
isbn_softcover978-3-642-26281-4
isbn_ebook978-3-642-04300-0Series ISSN 0945-6066 Series E-ISSN 2196-310X
issn_series 0945-6066
copyrightSpringer-Verlag Berlin Heidelberg 2010
The information of publication is updating

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0945-6066 s and is associated with reduced insulin activity both in periphery and brain. The insulin resistance syndrome underlies conditions such as Type 2 diabetes mellitus and hypertension, which are 978-3-642-26281-4978-3-642-04300-0Series ISSN 0945-6066 Series E-ISSN 2196-310X
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The Brain-insulin Connection, Metabolic Diseases and Related Pathologies,
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Insulin-Mediated Neuroplasticity in the Central Nervous System,
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