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Titlebook: Development of New Radical Cascades and Multi-Component Reactions; Application to the S Marie-Helene Larraufie Book 2014 Springer Internati

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樓主
發(fā)表于 2025-3-21 19:17:12 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Development of New Radical Cascades and Multi-Component Reactions
副標題Application to the S
編輯Marie-Helene Larraufie
視頻videohttp://file.papertrans.cn/270/269982/269982.mp4
概述Nominated as an outstanding Ph.D. thesis by the IPCM Université Pierre et Marie Curie, France.Honored with the French Chemical Society (SCF) - Organic Chemistry Section Ph. D. award for 2011.Presents
叢書名稱Springer Theses
圖書封面Titlebook: Development of New Radical Cascades and Multi-Component Reactions; Application to the S Marie-Helene Larraufie Book 2014 Springer Internati
描述In this dissertation, Marie-Hélène Larraufie develops original radical and pallado-catalyzed methodologies to enable the synthesis of several classes of bioactive nitrogen-containing heterocycles. New radical cascades employing the N-acylcyanamide moiety offer straightforward routes to quinazolinones and guanidines, as well as new insights into the mechanism of homolytic aromatic substitutions. In parallel, Larraufie expands the scope of visible light photoredox catalysis to the ring opening of epoxides and aziridines, thus providing new sustainable alternatives for the generation of radicals. Furthermore, in a collaborative effort with the Catellani group, the author investigates dual palladium/norbornene catalysis. First, she develops a C-amination coupling variant of the Catellani reaction with unprotected amines which provides an expeditious route to phenanthridines. Then, she examines the influence of the chelating effect on Pd(IV) intermediates reactivity with the help of experimental studies and DFT calculations. The work in this thesis has resulted in numerous publications in high impact journals.The clarity and depth of the experimental section will be useful for students
出版日期Book 2014
關鍵詞Aromatic Homolytic Substitution; Catellani Reaction; Cyanamides; Guanidines; Ortho Effect; Palladium IV; P
版次1
doihttps://doi.org/10.1007/978-3-319-01324-4
isbn_softcover978-3-319-37786-5
isbn_ebook978-3-319-01324-4Series ISSN 2190-5053 Series E-ISSN 2190-5061
issn_series 2190-5053
copyrightSpringer International Publishing Switzerland 2014
The information of publication is updating

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沙發(fā)
發(fā)表于 2025-3-21 21:40:31 | 只看該作者
Springer Theseshttp://image.papertrans.cn/d/image/269982.jpg
板凳
發(fā)表于 2025-3-22 00:27:40 | 只看該作者
Die Boltzmann-Transportgleichung,As we have seen in part Sect. 7.2, the incorporation of a .-aryl coupling reaction with unprotected amines in a Catellani sequence has never been reported. Only amides, imines and tosylated and acetylated anilines have been used successfully as coupling partners.
地板
發(fā)表于 2025-3-22 06:14:21 | 只看該作者
Results: New Partners for Ortho-Substituted Aryl Iodides in Palladium/Norbornene CocatalysisAs we have seen in part Sect. 7.2, the incorporation of a .-aryl coupling reaction with unprotected amines in a Catellani sequence has never been reported. Only amides, imines and tosylated and acetylated anilines have been used successfully as coupling partners.
5#
發(fā)表于 2025-3-22 09:54:15 | 只看該作者
Results: Developments of New Radical Cascades with ,-Acylcyanamidesr objectives were to test the reactivity of alkyl, vinyl and aminyl radicals in this process. Indeed, the use of alkyl and vinyl radical should provide us with a straightforward access to natural and biologically active quinazolinones; while the use of aminyl radicals should afford the first radical synthesis of guanidines.
6#
發(fā)表于 2025-3-22 12:55:18 | 只看該作者
Bibliographical Background: The Ortho Effect in The Catellani Reactionffolds, starting from simple precursors. In this context, Professor Marta Catellani has pioneered in the mid 1980s the utilization of norbornene in cooperation with palladium to achieve sequential C-halide and C–H activations via the formation of a five-membered alkylaromatic palladacycle.
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發(fā)表于 2025-3-22 19:43:53 | 只看該作者
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發(fā)表于 2025-3-23 01:00:13 | 只看該作者
9#
發(fā)表于 2025-3-23 03:28:29 | 只看該作者
Grundlagen der Grenzschicht-Meteorologier objectives were to test the reactivity of alkyl, vinyl and aminyl radicals in this process. Indeed, the use of alkyl and vinyl radical should provide us with a straightforward access to natural and biologically active quinazolinones; while the use of aminyl radicals should afford the first radical
10#
發(fā)表于 2025-3-23 05:31:24 | 只看該作者
Elektrische Eigenschaften der Halbleiter,actions are thus widely used in nature. Photosynthetic organisms absorb visible light by antenna proteins containing chromophores. Subsequent photon-induced electron transfers generate charge-separated states which are used to prepare various high-energy molecules required to fuel organisms. The pro
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