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Titlebook: Development and Recognition of the Transformed Cell; Mark I. Greene,Toshiyuki Hamaoka Book 1987 Plenum Press, New York 1987 biology.cell.c

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書目名稱Development and Recognition of the Transformed Cell
編輯Mark I. Greene,Toshiyuki Hamaoka
視頻videohttp://file.papertrans.cn/270/269925/269925.mp4
圖書封面Titlebook: Development and Recognition of the Transformed Cell;  Mark I. Greene,Toshiyuki Hamaoka Book 1987 Plenum Press, New York 1987 biology.cell.c
描述The study of the phenotypic and genetic features that characterize the malignant cell is a rapidly growing and changing field. Clearly new insights into the processes involved in normal and abnormal cell growth will facilitate our understanding of events relevant to cancer and cellular differentiation. Early studies on genetic fea- tures associated with cancer focused on chromosomal abnormalities that were observable in several human malignancies. The more recent examination of onco- genes and the proteins they encode has helped pinpoint many steps in different processes that might be involved in cancer. Immunologic studies of cancer have also developed from an imprecise series of investigations to a more detailed molecular examination of cell-surface struc- tures that can be recognized immunologically. In the course of the development of modern tumor immunology, it has become clear that many of the antigens that can be recognized appear to be the products of genes involved in cell growth. Fur- thermore, changes in the cell surface of malignant cells have often been found to include alteration of nonprotein constituents.
出版日期Book 1987
關(guān)鍵詞biology; cell; cell growth; cellular differentiation; cytogenetics; development; genetics; growth; leukemia;
版次1
doihttps://doi.org/10.1007/978-1-4613-1925-2
isbn_softcover978-1-4612-9070-4
isbn_ebook978-1-4613-1925-2
copyrightPlenum Press, New York 1987
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978-1-4612-9070-4Plenum Press, New York 1987
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Tuija Mainela,Vesa Puhakka,Sakari Sipolaproliferation of both tumor and normal cells. The first major analyses of the normal structure of the c-. gene and its altered structure in malignant cells followed the discovery that the c-. gene is involved in the chromosomal translocations observed in human Burkitt lymphomas and murine plasmacyto
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The Academy of International Businessrtain processes relevant to carcinogenesis. An important realization involved the recognition of the role of changes in DNA in the induction of cancer. In karyotypic studies of patients with chronic granulocytic leukemia, Nowell and Hungerford described chromosomal aberrations associated with a type
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https://doi.org/10.1007/978-3-319-48851-6s initially identified specific genes that were able to confer neoplastic properties on cells in tissue culture and that were responsible for tumor formation ... These genes were termed oncogenes. Subsequently, it was shown that genes closely related to retroviral oncogenes (protooncogenes) exist in
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