| 書目名稱 | Desmoid Tumors | | 編輯 | Charisse Litchman | | 視頻video | http://file.papertrans.cn/270/269135/269135.mp4 | | 概述 | First manuscript on desmoid tumors.World renowned authors.Encompasses topics of relevance to clinicians, scientific researchers and advocacy groups.Provides concrete guidance for treatment planning.Ad | | 圖書封面 |  | | 描述 | Desmoid Tumors (DT), also called Aggressive Fibromatoses, are a rare fibroblastic proliferative disease, with an incidence of 2 to 4 new cases per million people per year. Despite the absence of a metastatic potential, DT cause significant morbidity and at times mortality due to its locally invasive behaviour. The anatomical locations can be abdominal, extra-abdominal (often in the extremities) and intra-abdominal. This book is the first manuscript dedicated entirely to Desmoid Tumors. Written by prominent clinicians, researchers and advocacy group experts, patients and professionals alike will find this to be a comprehensive review. Clinical presentation, imaging guidelines and treatment paradigms are highlighted. Both the sporadic and heredity forms (Familial Adenomatous Polyposis) will be discussed. A thorough discussion on the unique issues in children with DT is included. A portion of the book will address the role of the APC gene, the β-catenin protein and the role of mutations in the genesis of DT. Emerging cutting edge research techniques will be revealed. Also included is a thoughtful discussion on the controversial labelling of Desmoid Tumors as benign and the consequence | | 出版日期 | Book 2012 | | 關鍵詞 | APC; Aggressive Fibromatosis; Desmoid Tumor; Familial Adenomatous Polyposis; β-catenin; surgical oncology | | 版次 | 1 | | doi | https://doi.org/10.1007/978-94-007-1685-8 | | isbn_softcover | 978-94-007-9303-3 | | isbn_ebook | 978-94-007-1685-8 | | copyright | Springer Science+Business Media B.V. 2012 |
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