Titlebook: Decoding Neural Circuit Structure and Function; Cellular Dissection Arzu ?elik,Mathias F. Wernet Book 2017 Springer International Publishi

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Book 2017ocusing on the ways it enhances our understanding of sensory processing. The authors focus on sensory systems (vision, olfaction), which are particularly powerful models for probing the development, connectivity, and function of neural circuits, to answer this question: How do individual nerve cells

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The Current State of the Neuroanatomy Toolkit in the Fruit Fly ,ulticellular species. Through molecular, developmental, histochemical, anatomical, and physiological experimentation, studies that incorporate fruit flies have had immediate biomedical impact relevant to neurobiology and neuropathology. . is one of the most well-established eukaryotic multicellular

Musculoskeletal

Retinal Connectomicsserial electron microscopy (EM) have placed a complete description of the synaptic connectivity of the mammalian retina within reach. These new tools have recently been used to densely reconstruct the largest piece of a mammalian retina to date. Connectivity mapping has also revealed an unprecedente

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Connectivity and Circuit Architecture Using Transsynaptic Tracing in Vertebratesof interconnected neurons that form information-processing neuronal circuits. Most brain areas contain diverse types of neurons with specific morphology, gene expression profiles, input/output connectivity, and physiological response profiles. One major goal of neuroscience is to decipher connection

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Live Imaging of Connectivity in Developing Neural Circuits in ,ain development reveals stochastic and dynamic processes that help to understand functional constraints in the adult circuitry. In the first part of this chapter, we will explore what live imaging tells us about how dynamic processes create and constrain circuit specificity. In the second part of th

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Manipulation of Neural Circuits in , Larvae development of powerful genetic tools to monitor and to manipulate the activity of identified neurons in the fly nervous system. However, establishing causal relationships between the activity of a given neuron and the expression of a behavior remains challenging both at a technical and at a concep

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Targeted Manipulation of Neuronal Activity in Behaving Adult Fliesuits to behavior. Wide interest in studying principles of neural circuit function using the fruit fly . has fueled the construction of an extensive transgenic toolkit for performing such neural manipulations. Here we describe approaches for using these tools to manipulate the activity of specific ne