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Titlebook: Damage-Associated Molecular Patterns in Human Diseases; Volume 3: Antigen-Re Walter Gottlieb Land Book 2023 The Editor(s) (if applicable) a

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書目名稱Damage-Associated Molecular Patterns in Human Diseases
副標題Volume 3: Antigen-Re
編輯Walter Gottlieb Land
視頻videohttp://file.papertrans.cn/261/260308/260308.mp4
概述Describes current knowledge of the role of DAMPs in inducing immune responses.Explores the significance of DAMPs in a wide range of human diseases.Explains how innovative data from immunity and inflam
圖書封面Titlebook: Damage-Associated Molecular Patterns in Human Diseases; Volume 3: Antigen-Re Walter Gottlieb Land Book 2023 The Editor(s) (if applicable) a
描述.The core of this three-volume book deals with damage-associated molecular patterns abbreviated “DAMPs”, which are unique molecules that save life and fight for survival of all organisms on this planet by triggering robust inflammatory/immune defense responses upon any injury, including those caused by pathogens such as viruses and bacteria. However, these molecules also have a dark side: when produced in excess upon severe insults, they can trigger serious human diseases...The three volumes present current understanding of the importance of DAMP-promoted immune responses in the etiopathogenesis of human diseases and explore how this understanding is impacting diagnosis, prognosis, and future treatment. This third volume addresses the potential of DAMPs in clinical practice, as therapeutic targets and therapeutics, by focusing on a description of antigen-related diseases, which are pathogenetically dominated by DAMPs, that is, infectious and autoimmune disorders and allograftrejection (as an undesired function of these molecules), as well as tumor rejection (as the desired function of these molecules)...The book is written for professionals from all medical and paramedical discipli
出版日期Book 2023
關鍵詞Innate Immunity; Autoimmune diseases; Metabolic syndrome; Traumatic disorders; Host defense; Covid-19; Vac
版次1
doihttps://doi.org/10.1007/978-3-031-21776-0
isbn_softcover978-3-031-21778-4
isbn_ebook978-3-031-21776-0
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl
The information of publication is updating

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Virulence of Pathogens and the Counteracting Responses of the Host parasites, while the second part deals with the counteracting host defense responses against the various virulence factors, such as initiation of cell-autonomous stress responses and—if these defensive actions fail—the decision of cells to undergo regulated cell death as a prolific source of DAMPs
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Basic Trajectories in Autoimmunity mechanisms of central and peripheral T cell and B cell tolerance induction to self/self antigens. The centerpiece of this overview is the presentation of the danger/injury model of tolerance induction, which states that it is the responsibility of the peripheral bodily tissue, rather than the innat
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DAMPs in Organ-Specific Autoimmune Diseaseso prototypical disorders of this group, multiple sclerosis and type 1 diabetes mellitus. The pathogenesis of both disorders is complex and orchestrated by an interrelationship between environmental triggers, genetic predisposition, and epigenetic modifications. In view of the danger/injury model and
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Approaching the DAMPome: Evolution in Medicine?d that can be qualified as DAMPs or SAMPs, and the discoveries are far from over. Accordingly, the observations and findings about their chemical structure, nature, and function in biomedicine, as briefly addressed in this book, can only be considered as a “snapshot narrative.” This is all the more
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