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Titlebook: DNA-Protein Interactions; Principles and Proto Beno?t P. Leblanc,Sébastien Rodrigue Book 2015Latest edition Springer Science+Business Media

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書目名稱DNA-Protein Interactions
副標(biāo)題Principles and Proto
編輯Beno?t P. Leblanc,Sébastien Rodrigue
視頻videohttp://file.papertrans.cn/261/260229/260229.mp4
概述Includes fully updated, cutting-edge methods and protocols for studying protein-DNA interactions.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation a
叢書名稱Methods in Molecular Biology
圖書封面Titlebook: DNA-Protein Interactions; Principles and Proto Beno?t P. Leblanc,Sébastien Rodrigue Book 2015Latest edition Springer Science+Business Media
描述.This fourth edition reflects the most recent technical advances in DNA-protein interaction research. With fully updated chapters that describe techniques proven by their continuous value, the volume also many new chapters have been added that mostly deal with larger-scale experiments, reflecting recent advances in "big biology", combining to offer a very useful compendium of protocols allowing readers to delve into the intricacies of protein-DNA interaction at levels ranging from the very small (as in the case of single-molecule FRET) to the very complex (as with circular chromatin conformation capture or 4C). Written for the highly successful .Methods in Molecular Biology. series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls..Authoritative and up-to-date, .DNA-Protein Interactions: Principles and Protocols, Fourth Edition. will aid researchers in continuing the incredible progress made in this vital area of study..
出版日期Book 2015Latest edition
關(guān)鍵詞Chromatin immunoprecipitation; Circular chromatin conformation capture (4C); Gene expression regulatio
版次4
doihttps://doi.org/10.1007/978-1-4939-2877-4
isbn_softcover978-1-4939-4945-8
isbn_ebook978-1-4939-2877-4Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightSpringer Science+Business Media New York 2015
The information of publication is updating

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Single-Molecule Approaches for the Characterization of Riboswitch Folding Mechanisms,l changes, thus enabling to deduce complex riboswitch folding pathways. Herein, we show how to employ sm-FRET to study the folding pathway of the .-adenosylmethionine (SAM) and how this can be used to understand very specific conformational changes that are at the heart of riboswitch regulation mech
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B. Scherrer,M. Dojat,F. Forbes,C. Garbayhese analyses were combined with 3-D models of the available structures of portions of the activator protein and B-form DNA to obtain a 3-D picture of the protein relative to the DNA. Finally, the Molsoft program was used to refine the position, revealing the architecture of the protein–DNA within t
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