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Titlebook: DNA Repair Protocols; Daryl S. Henderson Book 1999 Humana Press 1999 DNA.Ligation.PCR.Quantitative PCR.cell lines.genes.saccharomyces cere

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發(fā)表于 2025-3-21 16:28:09 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱DNA Repair Protocols
編輯Daryl S. Henderson
視頻videohttp://file.papertrans.cn/261/260181/260181.mp4
叢書名稱Methods in Molecular Biology
圖書封面Titlebook: DNA Repair Protocols;  Daryl S. Henderson Book 1999 Humana Press 1999 DNA.Ligation.PCR.Quantitative PCR.cell lines.genes.saccharomyces cere
描述The field of eukaryotic DNA repair is enjoying a period of remarkable growth and discovery, fueled by technological advances in molecular bi- ogy, protein biochemistry, and genetics. Notable achievements include the molecular cloning of multiple genes associated with classical human repair disorders, such as xeroderma pigmentosum, Cockayne syndrome, and ataxia telangiectasia; elucidation of the core reaction of nucleotide excision repair (NER); the discovery that certain NER proteins participate not only in repair, but also in transcription; recognition of the crucial role played by mismatch repair processes in maintenance of genome stability and avoidance of cancer; the findings that the tumor suppressor protein p53 is mutated in many types of cancer, and has a key role in directing potentially malignant, genotoxin-d- aged cells towards an apoptotic fate; and the discovery and elaboration of DNA damage (and replication) checkpoints, which placed repair phenomen- ogy firmly within a cell-cycle context. Of course, much remains to be learned about DNA repair. To that end, DNA Repair Protocols: Eukaryotic Systems is about the tools and techniques that have helped propel the DNA repair
出版日期Book 1999
關(guān)鍵詞DNA; Ligation; PCR; Quantitative PCR; cell lines; genes; saccharomyces cerevisiae
版次1
doihttps://doi.org/10.1385/1592596754
isbn_softcover978-1-61737-196-7
isbn_ebook978-1-59259-675-1Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightHumana Press 1999
The information of publication is updating

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The Difficult Primary Total Hip Arthroplastyent of a patient to a complementation group has been achieved by using the somatic cell fusion procedure followed by analysis of UDS or recovery of RNA synthesis (RRS) after ultraviolet (UV) irradiation (.,.).
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Novel Complementation Assays for DNA Repair-Deficient Cellsent of a patient to a complementation group has been achieved by using the somatic cell fusion procedure followed by analysis of UDS or recovery of RNA synthesis (RRS) after ultraviolet (UV) irradiation (.,.).
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Mismatch Repair Assay However resistant subpopulations can arise spontaneously, and these subpopulations have been shown to be mismatch repair defective (.,.). To determine unambiguously that both HNPCC (.) and alkylation tolerance were owing to mismatch repair-defects, it was crucial to prove that mismatch repair activity was reduced or eliminated in mutant cells.
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Analysis of Th1/Th2 T-Cell Subsets availability of thousands of mutants as well as the existence of a physical map whose sequencing (over 82 Mb finished at present) is scheduled for completion in 1999. Developmental studies have been advantaged by the animal’s transparent nature, facilitating complete elucidation of . largely invariant cell lineage.
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