Titlebook: DNA Repair Protocols; Prokaryotic Systems Pat Vaughan Book 2000 Humana Press 2000

責(zé)怪

DNA Repair Protocols978-1-59259-068-1Series ISSN 1064-3745 Series E-ISSN 1940-6029

泄露

Fatten

馬籠頭

The , Vsr Endonucleasene to thymine (reviewed in .). By making a nick 5′ of the T, Vsr provides a site for DNA polymerase I to start the removal of the mismatched base, along with several nucleotides on its 3′ side. Resynthesis of the missing bases by the polymerase restores the correct C.G basepair and completes the process of very short patch (VSP) repair.

慷慨援助

Use of Uracil DNA Glycosylase in the Detection of Known DNA Mutations and Polymorphismsidemiology, and rapid identification of various traits in eukaryotic and prokaryotic organisms. An optimum system for sequence variation detection needs to offer specificity, sensitivity, flexibility, as well as ease of use and allow rapid and high throughput of samples.

粗語(yǔ)

Helmuth Deicher,Leo-Clemens SchulzDetection of unknown mutations and polymorphisms is a central ingredient in disease gene discovery and genetic diagnosis in addition to polymorphism discovery and genotyping programs. An optimum system for detection of sequence variation needs to offer specificity, sensitivity, flexibility, as well as ease of use.

接合

修飾語(yǔ)

M. E. Safar,G. M. London,Y. A. Weissable products of oxidative DNA damage. The formation of GO in DNA, if not repaired, can lead to misincorporation of A opposite to the GO lesion and result in G:C to T:A transversions (.–.). In ., a family of enzymes, MutY, MutM, and MutT, is involved in defending against the mutagenic effects of GO

臭了生氣

Haphazard

Bestimmung des individuellen Blutdruckes lesions. DNArepair mechanisms have evolved to counteract the deleterious effects of DNA damage. One such repair mechanism is Base Excision Repair (BER). BER is a repair process initiated by a class of enzymes called glycosylases. These enzymes catalyze the hydrolysis of the N-glycosidic bond, there