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Titlebook: DNA Repair Disorders; Chikako Nishigori,Kaoru Sugasawa Book 2019 Springer Nature Singapore Pte Ltd. 2019 DNA repair.Xertoderma pigmentosum

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發(fā)表于 2025-3-21 19:41:21 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱DNA Repair Disorders
編輯Chikako Nishigori,Kaoru Sugasawa
視頻videohttp://file.papertrans.cn/261/260177/260177.mp4
概述Presents clinical features together with the pathogenesis of DNA repair disorders such as Xertoderma Pigmentosum (XP).Provides detailed information on clinical features from more than 100 patients wit
圖書封面Titlebook: DNA Repair Disorders;  Chikako Nishigori,Kaoru Sugasawa Book 2019 Springer Nature Singapore Pte Ltd. 2019 DNA repair.Xertoderma pigmentosum
描述.This book focuses on the clinical aspects of DNA repair disorders. Nucleotide excision repair is an important pathway for humans, as it is involved in biologically fundamental functions. This work presents clinical features together with the pathogenesis of DNA repair disorders such as Xertoderma Pigmentosum (XP). Studies on animal models are included as well. ..Clinical feature characteristics of each clinical subtype of XP are depicted according to the genotype, giving accurate and detailed information about the clinical features in terms of gene alterations, change of protein structure, and dysfunction in some of the repair pathways. This book is unique in that it provides detailed information on clinical features from more than 100 patients with XP-A, which is characterized by very severe manifestation of skin photosensitivity and neurological dysfunction. It will give readers important knowledge for understanding the concept and molecular mechanisms of DNA repair disorders. It also describes how to treat and care for patients with XP based on vast experience in clinical practice...DNA Repair Disorders. will be a useful resource not only for physicians and basic scientists who
出版日期Book 2019
關(guān)鍵詞DNA repair; Xertoderma pigmentosum; Nucletotide excision repair; Cockayne syndromes; Trichothiodystrophy
版次1
doihttps://doi.org/10.1007/978-981-10-6722-8
isbn_ebook978-981-10-6722-8
copyrightSpringer Nature Singapore Pte Ltd. 2019
The information of publication is updating

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Artivism and the Spirit of Avant-Garde Art carcinoma and malignant melanoma. The frequency of these skin cancers in patients with XP-A has decreased in these 20?years, and ages of onset of developing skin cancers are much older than those previously observed, which is greatly attributed to the education of sun protection for the patients wi
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Artivism and the Spirit of Avant-Garde Artage, disturbed metabolism of monoamines and melatonin, vascular changes in the brain, and/or pathology of oligodendrocytes and microglial cells may be involved in neurodegeneration, suggesting the possibility of treatments with free radical scavengers, monoaminergic agents, and/or melatonin. We repo
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發(fā)表于 2025-3-22 15:24:56 | 只看該作者
Art in the City, the City in Art TTD clinical symptoms except for clinical and cellular photosensitivity that, however, in TTD does not result in increased carcinogenesis. The recent finding that alterations in the β-subunit of the basal transcription factor TFIIE result in the non-photosensitive form of TTD highlights the relevan
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Aesthetics and Educational Value Strugglesθ has an important role in an alternative end-joining repair pathway for DNA double-strand breaks, protecting against genomic instability. PrimPol is a protein with DNA polymerase and primase activities that is capable of initiating . DNA/RNA synthesis and that also has the capacity to bypass modifi
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Disorders with Deficiency in TC-NER: Molecular Pathogenesis of Cockayne Syndrome and UV-Sensitive Sas well as premature ageing, whereas UV.S individuals only show milder cutaneous abnormalities, such as hypersensitivity to UV light. The molecular basis for the difference in the clinical features remains unclear. In this chapter, we will specifically describe the historical progress and recent fin
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Hearing Impairment in Xeroderma Pigmentosum: Animal Models and Human Studies,omic stress, such as reactive oxygen species (ROS), which leads to early onset of sensorineural hearing loss. Regular audiometric monitoring of the hearing status of patients with XP to identify the need for auditory interventions, such as hearing aids, is important for maintaining their quality of
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