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Titlebook: DNA Methylation: Development, Genetic Disease and Cancer; Walter Doerfler,Petra B?hm Book 2006 The Editor(s) (if applicable) and The Autho

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發(fā)表于 2025-3-25 04:42:19 | 只看該作者
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Precipitation and Evapotranspiration represented by LINE-1, nonautonomous small interspersed nuclear elements (SINEs) are primarily represented by ALUs, and LTR retrotransposons by several families of human endogenous retroviruses (HERVs). The vast majority of LINE and HERV elements are densely methylated in normal somatic cells and c
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Walter Doerfler,Petra B?hmIncludes supplementary material:
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The Regulation of Chromatin and DNA-Methylation Patterns in Blood Cell Development,ial gene expression is also the basis for the alterations in the developmental potential of differentiating cells. However, the molecular details concerning how this is achieved are still poorly understood. The haematopoietic system has for many years served as an excellent model system to study how
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發(fā)表于 2025-3-26 15:15:21 | 只看該作者
Methylation Dynamics in the Early Mammalian Embryo: Implications of Genome Reprogramming Defects foevelopment. The paternal genome is actively demethylated within a few hours after fertilization in the mouse, rat, pig, bovine, and human zygote, whereas the maternal genome is passively demethylated by a replication-dependent mechanism after the two-cell embryo stage. These genome-wide demethylatio
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