Titlebook: DNA Methylation: Basic Mechanisms; Walter Doerfler (Prof. Dr.),Petra B?hm Book 2006 The Editor(s) (if applicable) and The Author(s), under

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Aria, acqua, terra e fuoco - Volume Ithylcytosine preferentially undergoes sunlight-induced pyrimidine dimer formation. Certain polycyclic aromatic hydrocarbons form guanine adducts and induce G to T transversion mutations with high selectivity at mCpG sequences.

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https://doi.org/10.1007/978-88-470-2547-9 such as p53 and the retinoblastoma protein, causing cancer. We also examine the specific repair enzymes involved, namely the endonuclease Vsr in . and two members of the uracil DNA glycosylase (UDG) superfamily in mammals, TDG and MBD4. Repair brings its own problems, since it will require remethyl

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Molecular Enzymology of Mammalian DNA Methyltransferases

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Familial Hydatidiform Molar Pregnancy: The Germline Imprinting Defect Hypothesis?

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DNA Methylation in Plantsted. Cytosine DNA methylation in plants is more rich and diverse compared with animals. It is carried out by the families of specific enzymes that belong to at least three classes of DNA methyltransferases. Open reading frames (ORF) for adenine DNA methyltransferases are found in plant and animal ge

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De Novo Methylation, Long-Term Promoter Silencing, Methylation Patterns in the Human Genome, and Con DNA methylation, we focused mainly on the human genome. The following topics in DNA methylation will be treated in detail: (1) The de novo methylation of integrated foreign genomes; (2) the long-term gene silencing effect of sequence-specific promoter methylation and its reversal; (3) the propertie

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