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Titlebook: DNA Damage and Repair; Volume 2: DNA Repair Jac A. Nickoloff,Merl F. Hoekstra Book 1998 Springer Science+Business Media New York 1998 Activ

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書目名稱DNA Damage and Repair
副標(biāo)題Volume 2: DNA Repair
編輯Jac A. Nickoloff,Merl F. Hoekstra
視頻videohttp://file.papertrans.cn/261/260137/260137.mp4
叢書名稱Contemporary Cancer Research
圖書封面Titlebook: DNA Damage and Repair; Volume 2: DNA Repair Jac A. Nickoloff,Merl F. Hoekstra Book 1998 Springer Science+Business Media New York 1998 Activ
描述Cutting edge reviews by leading researchers illuminate key aspects of DNA repair in mammalian systems and its relationship to human genetic disease and cancer. Major topics include UV and X-Ray repair, repair of chemical damage, recombinational repair, mismatch repair, transcription-repair coupling, and the role of DNA repair in disease prevention. Extensive up-to-date references and rigorous peer-review of each chapter make this volume definitive and bring it to the active frontiers of research.
出版日期Book 1998
關(guān)鍵詞Activation; DNA; Regulation; Translation; biochemistry; genes; recombination; transcription
版次1
doihttps://doi.org/10.1007/978-1-59259-455-9
isbn_softcover978-1-4757-5015-7
isbn_ebook978-1-59259-455-9
copyrightSpringer Science+Business Media New York 1998
The information of publication is updating

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Nature of Lesions Formed by Ionizing Radiation,e the source of higher-level damage (killing, mutation, transformation). Of course, the damage that is produced initially by radiation is subject to enzymatic repair, and hence, to assess the ability of a cell to repair the change, it is important to know the identities of the types of damage. Produ
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Biochemistry of Mammalian DNA Mismatch Repair,ative errors and to protect their DNA from various types of damage .. Mismatch repair systems enhance the fidelity of DNA replication by correcting replicative errors skipped by the DNA polymerase during editing. Mutants defective in mismatch repair enzymes are marked by genome instability and/or mu
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Role of HMG and Other Proteins in Recognition of Cisplatin DNA Damage, of DNA damage. Presumably, damage recognition is mediated by specific damage-recognition proteins (DRPs), which recognize particular types of DNA lesions and/or specific DNA conformations resulting from adduct formation, such as that following binding of .-diaminedichloroplatinum (II) (cisplatin or
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TFIIH,iscovery that one of its subunits was XP-B (ERCC3), a protein known to be involved in nucleotide excision repair (NER; . Chapter 18), put it at the focus of both transcription and DNA repair fields. Further studies in humans and yeast have shown that additional subunits of TFIIH, including XP-D, p62
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Mammalian DNA Repair and the Cellular DNA Polymerases,NA, damaged DNA sites must be repaired, and organisms have several DNA repair pathways that are vital in maintaining genome stability. Each individual DNA repair pathway (i.e., error-free repair, base excision repair, nucleotide excision repair, and so forth) is generally similar throughout nature,
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