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Titlebook: DJ-1/PARK7 Protein; Parkinson’s Disease, Hiroyoshi Ariga,Sanae‘M. M. Iguchi-Ariga Book 2017 Springer Nature Singapore Pte Ltd. 2017 DJ-1.Pa

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發(fā)表于 2025-3-21 20:07:38 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱DJ-1/PARK7 Protein
副標(biāo)題Parkinson’s Disease,
編輯Hiroyoshi Ariga,Sanae‘M. M. Iguchi-Ariga
視頻videohttp://file.papertrans.cn/261/260097/260097.mp4
概述Covers various oxidative stress-related diseases, including cancer, neurodegenerative diseases, and type 2 diabetes as well as male infertility.Broadens the understanding of the various uses of DJ-1 s
叢書名稱Advances in Experimental Medicine and Biology
圖書封面Titlebook: DJ-1/PARK7 Protein; Parkinson’s Disease, Hiroyoshi Ariga,Sanae‘M. M. Iguchi-Ariga Book 2017 Springer Nature Singapore Pte Ltd. 2017 DJ-1.Pa
描述This book reviews the functions and roles of DJ-1 in various oxidative stress-related diseases and applications of DJ-1 and its binding compounds to the diseases. The?.DJ-1?.gene was first found to be a novel oncogene in 1997 and later, in 2003, also found to be a causative gene for a familial form of Parkinson’s disease (PD), park7. The?.DJ-1.?gene is therefore the first gene discovered that is known to cause cancer and neurodenegerative diseases, including PD. The research field has expanded as the research has developed. Thus this volume begins with a general introduction of?.DJ-1., and explains the history and research development to understand the following chapters. Those chapters present the roles of?.DJ-1.?in various oxidative stress-related diseases such as neurodegenerative diseases, as well as cancer, diabetes, and fertility. Moreover, several chapters present evidence that DJ-1 is useful for therapeutic strategies against these diseases. The reader willdiscover that DJ-1 is a promising protein both for basic cell biology and for the mechanism and therapy for oxidative stress-related diseases.?.
出版日期Book 2017
關(guān)鍵詞DJ-1; Parkinson’s disease; Cancer; Type 2 diabetes; Male infertility; Oxidative stress; Mitochondria; Signa
版次1
doihttps://doi.org/10.1007/978-981-10-6583-5
isbn_softcover978-981-13-4908-9
isbn_ebook978-981-10-6583-5Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightSpringer Nature Singapore Pte Ltd. 2017
The information of publication is updating

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發(fā)表于 2025-3-21 23:40:11 | 只看該作者
Expression of DJ-1 in Cancer Cells: Its Correlation with Clinical Significance,y, and drug sensitivity. Thus, DJ-1 plays a critical role in cancer. Although DJ-1 has an important role within cancer cells, cancer cells secrete DJ-1 outside the cells. DJ-1 may serve as a tumor marker that can be detected from an early stage in the blood, secretory fluids, ascites, or pleural effusion.
板凳
發(fā)表于 2025-3-22 00:29:03 | 只看該作者
地板
發(fā)表于 2025-3-22 06:50:46 | 只看該作者
Fish Lectins in Host–Pathogen Interactiony, and drug sensitivity. Thus, DJ-1 plays a critical role in cancer. Although DJ-1 has an important role within cancer cells, cancer cells secrete DJ-1 outside the cells. DJ-1 may serve as a tumor marker that can be detected from an early stage in the blood, secretory fluids, ascites, or pleural effusion.
5#
發(fā)表于 2025-3-22 09:29:21 | 只看該作者
https://doi.org/10.1007/1-4020-5368-1also plays a critical role in tumor development and progression. In this review, we provide an overview of current knowledge concerning the role and the mechanism of DJ-1 in cancer and also discuss the possibility of DJ-1 as a therapeutic target against cancer.
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發(fā)表于 2025-3-22 14:49:31 | 只看該作者
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發(fā)表于 2025-3-23 01:16:22 | 只看該作者
Introduction/Overview,ve rise to the common mechanism among these diseases. Furthermore, secreted DJ-1 levels in serum and DJ-1-binding compounds will be a diagnostic biomarker and therapeutic drug for neurodegenerative diseases, respectively.
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發(fā)表于 2025-3-23 05:05:36 | 只看該作者
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發(fā)表于 2025-3-23 09:31:38 | 只看該作者
Sources and Age of Aquatic Humusnction primarily as a redox-responsive protein that may act as a sensor for imbalances in cellular redox state. Because mutations in human DJ-1 cause certain types of heritable Parkinson’s disease, the role of oxidative posttranslational modifications and pathogenic mutations in human DJ-1 is emphasized in the latter sections of this chapter.
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