Titlebook: Cytomegaloviruses; James K. McDougall (Research Professor of Patholog Conference proceedings 1990 The Editor(s) (if applicable) and The Au

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Immediate-Early Transcription Regulation of Human Cytomegalovirusns of human cytomegalovirus (HCMV) (W. and S. 1982; M.D. and S. 1983; W. et al. 1984; D.M. 1981). The IE RNA of HCMV arises from a few distinct regions of the viral genome. The region of highest transcriptional activity is localized between map units 0.66 and 0.77 in the genomes of all HCMV strains

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Immune Response to Human Cytomegalovirus InfectionV vaccine is dependent upon progress in studies of both the virology and immunology of CMV. In this review, I will first summarize what is currently known about the protein structure of human CMV. In that section I will focus on those proteins and glycoproteins that have either been characterized ac

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0070-217X t and severity of disease. Cytomegaloviruses have the largest genomes in the herpes- virus family, approximately 240 kilo base pairs, providing a potential codi978-3-642-74982-7978-3-642-74980-3Series ISSN 0070-217X Series E-ISSN 2196-9965

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Fear and Loathing in the Russian Empire “immediate early” (IE), follows entry of the virus into the host cell. It is independent of de novo synthesis of viral proteins. In general, a second (“early”) phase follows, when a number of regulatory proteins and viral enzymes are synthesized. During the third phase (“l(fā)ate”), which begins with o

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The Nazi Analogy in , Reader Commentss appears to be able to infect a number of cell types in vivo including epithelial cells, neural cells, endothelial cells, mesenchymal cells, and some subclasses of leukocytes, although viral gene expression may be limited in some of these cells. Within the past 30 years, this virus has been recogni

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Does Defining Racism Help Overcome It? site of latency and the molecular mechanisms involved in the establishment and maintenance of latent virus in the cell are unknown for HCMV. In this chapter, we will discuss experimental approaches to identifying cell types naturally infected in the human host by HCMV. We will examine cell culture