Titlebook: Cytokines in Human Health; Immunotoxicology, Pa Robert V. House,Jacques Descotes Book 2007 Humana Press 2007 Chemokine.Endoplasmatisches Re

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Cytokine-Induced Vascular Leak Syndrome,esulting in tissue edema and, ultimately, multiple organ failure. The most frequent clinical manifestations of cytokine-induced VLS include weight gain, edema, oliguria, hypotension, and dyspnea. Respiratory insufficiency requiring mechanical ventilation and hypotension requiring pressor support hav

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Evaluation of Antibodies in Clinical Trials of Cytokines,contribute to a cytokine being immunogenic, such as aggregation. The understanding of cytokine immunogenicity requires a thorough knowledge of the antibody testing that was performed. Some of the methods used to test for antibodies against cytokines are the enzyme-linked immunosorbent assay, radioim

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Cytokines and Pharmacokinetic Drug Interactions,dominantly through cytokine-mediated pathways. Most of the major cytokines, including interleukin (IL)-1α, IL-1β, IL-2β, IL-6, tumor necrosis factor-α, inteferon-α, inteferon-γ, and transforming growth factor-β, are known to downregulate the major forms of cytochrome P450 and P-glycoprotein. In most

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