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Titlebook: Cytokines and Autoimmune Diseases; Vijay K. Kuchroo,Nora Sarvetnick,Lindsay B. Nichol Book 2002 Springer Science+Business Media New York 2

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書目名稱Cytokines and Autoimmune Diseases
編輯Vijay K. Kuchroo,Nora Sarvetnick,Lindsay B. Nichol
視頻videohttp://file.papertrans.cn/243/242637/242637.mp4
概述Includes supplementary material:
圖書封面Titlebook: Cytokines and Autoimmune Diseases;  Vijay K. Kuchroo,Nora Sarvetnick,Lindsay B. Nichol Book 2002 Springer Science+Business Media New York 2
描述Leading researchers synthesize scattered experimental data to help develop an intimate understanding of how cytokines and chemokines are involved in the pathogenesis of autoimmune diseases. The many chapters offer critical reviews the basic mechanisms controlling cytokine induction and regulation, as well as the resulting production of proinflammatory and anti-inflammatory cytokines, the former of which induces organ-specific autoimmune diseases. From the vantage of these insights, they address the role of cytokines in a wide variety of autoimmune diseases, uvetis, encephalomyelitis, multiple sclerosis, human type 1 diabetes, rheumatoid arthritis, SLE, and myasthenia gravis. Authoritative and state-of-the-art, Cytokines and Autoimmune Diseasehighlights the enormous therapeutic potential of cytokine modulation in the treatment of autoimmune disease.
出版日期Book 2002
關(guān)鍵詞Chemokine; T cell; autoimmune disease; autoimmunity; cytokine; diseases; pathogenesis; resistance
版次1
doihttps://doi.org/10.1007/978-1-59259-129-9
isbn_softcover978-1-61737-225-4
isbn_ebook978-1-59259-129-9
copyrightSpringer Science+Business Media New York 2002
The information of publication is updating

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Variant Ligands, Altered T Cell Receptor Signaling, Hierarchical Response Thresholds, and CD4+ Effecire is produced by selection in the thymus of precursor T cells bearing clonally distributed TCR, based on the nature of signals generated by receptor interaction with ligands comprised of self-peptides bount to major histocompatibility complex (MHC) class I or class II molecules (.). In the periphe
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CD1d-Restricted NK T Cells and Autoimmunityc studies demonstrate that a combinatorial admixture of susceptibility and protective genes influences development of disease (.). Longitudinal studies on twins or large cohorts of at-risk individuals indicate that many high-risk subjects do not develop overt disease (., .). In fact, once the nefari
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Role of T Cell Death and Cytokines in Autoimmunity total number of immune cells can increase is often attributalbe to a 1000- to 50,000-fold expansion of the lymphocytes specific for the antigens of the microbe. At the same time, the immune system continuously generates new lymphocytes, each specific for a different antigen, in the hope that one or
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The Role of Cytokines in Induction and Regulation of Autoimmune Uveitised to have an autoimmune or immune-mediated origin. It can affect the front, middle, or back part of the eye, and is then termed anterior, intermediate, and posterior uveitis, respectively. A schematic drawing of a human eye is shown in Fig. 1. The uveitic conditions that affect the back of the eye
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