Titlebook: Cytokine Knockouts; Giamila Fantuzzi Book 2003Latest edition Springer Science+Business Media New York 2003 Chemokine.Immune System.autoimm

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https://doi.org/10.1007/978-3-030-84514-8ogy research. This is a fast-growing area that is expanding dramatically as genetically modified animals for cytokines, their receptors, or signalling components become available. We have focused primarily on the best-known cytokines (IL-1, IL-6, TNF-α, IL-10 & IL-4) simply to highlight the contribu

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Culture, Cancer, and Communication in Italy.). The original identification of IL-1 as an endogenous pyrogen, lymphocyte-activating factor, hemopoietin-1, and osteoclast-activating factor, serves to demonstrate its pleiotropic activity (.). IL-1, produced by cell types such as macrophages, monocytes, and synovial lining cells, induces inflamm

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About the Origins of this Volumeal killer (NK) cell development and are responsible for X-linked severe combined immunodeficiency disease (X-SCID). Considerable attention has been paid to how the lack of γc expression and signaling results in failed lymphocyte development. However, γc is also an essential ligand binding subunit fo

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Robert L. Rubinstein,J. Keith,D. Wielandnd blood in response to allergic and parasitic stimuli. IL-5 also plays a central role in regulating baseline blood and tissue eosinophil numbers but is not essential for eosinophil development or migration. Thus, eosinophil accumulation into allergic tissues should not be viewed as a process that i

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