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Titlebook: Cytokine Knockouts; Giamila Fantuzzi Book 2003Latest edition Springer Science+Business Media New York 2003 Chemokine.Immune System.autoimm

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發(fā)表于 2025-3-21 18:33:47 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書(shū)目名稱Cytokine Knockouts
編輯Giamila Fantuzzi
視頻videohttp://file.papertrans.cn/243/242630/242630.mp4
概述Includes supplementary material:
叢書(shū)名稱Contemporary Immunology
圖書(shū)封面Titlebook: Cytokine Knockouts;  Giamila Fantuzzi Book 2003Latest edition Springer Science+Business Media New York 2003 Chemokine.Immune System.autoimm
描述Carrying on the high standards of the much praised first edition (Durum and Muegge, Cytokine Knockouts, 1998), Giamila Fantuzzi and a panel of experts have generated completely new chapters to reflect the use of many novel mouse strains and the hundreds of recent studies on cytokine physiology. Comprehensive reviews of the numerous often-surprising results obtained using cytokine knockout mice are provided, along with much important information about cytokine biology and physiology. For those not familiar with cytokine research, the authors present a critical discussion of the advantages and disadvantages of using cytokine knockout mice in various fields of research.
出版日期Book 2003Latest edition
關(guān)鍵詞Chemokine; Immune System; autoimmune disease; migration; physiology
版次2
doihttps://doi.org/10.1007/978-1-59259-405-4
isbn_softcover978-1-61737-415-9
isbn_ebook978-1-59259-405-4
copyrightSpringer Science+Business Media New York 2003
The information of publication is updating

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發(fā)表于 2025-3-21 23:25:21 | 只看該作者
Molecular Basis for Binding Multiple Cytokines by γcr γc-dependent cytokine receptors. Molecular modeling in conjunction with site-directed mutagenesis of γc indicates that a common mechanism is responsible for the ability of γc to bind multiple cytokines. This notion is related to instances in which mutations in the extracytoplasmic region of γc resulted in X-SCID.
板凳
發(fā)表于 2025-3-22 01:44:58 | 只看該作者
Book 2003Latest editionbout cytokine biology and physiology. For those not familiar with cytokine research, the authors present a critical discussion of the advantages and disadvantages of using cytokine knockout mice in various fields of research.
地板
發(fā)表于 2025-3-22 06:14:06 | 只看該作者
ed, along with much important information about cytokine biology and physiology. For those not familiar with cytokine research, the authors present a critical discussion of the advantages and disadvantages of using cytokine knockout mice in various fields of research.978-1-61737-415-9978-1-59259-405-4
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發(fā)表于 2025-3-22 12:05:23 | 只看該作者
Global Maternal and Child Healthby these studies belong almost exclusively to the innate immunity compartment. This strengthens the view that disturbed recruitment of innate immunity mechanisms is at least as important in the pathogenesis of the autoimmune disease process as the antigen-specific reaction towards self.
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發(fā)表于 2025-3-22 15:14:47 | 只看該作者
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發(fā)表于 2025-3-22 22:02:32 | 只看該作者
The Use of Cytokine Knockouts in Animal Models of Autoimmune Diseaseby these studies belong almost exclusively to the innate immunity compartment. This strengthens the view that disturbed recruitment of innate immunity mechanisms is at least as important in the pathogenesis of the autoimmune disease process as the antigen-specific reaction towards self.
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發(fā)表于 2025-3-23 01:58:32 | 只看該作者
A Unique Role for IL-2 in Self-Toleranceection of autoreactive CD4 T-cells is being discussed. In conclusion, it has become clear that while redundant as a T-cell growth factor, IL-2 serves a unique role as a negative regulator of the immune system with an essential task in maintaining self tolerance.
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發(fā)表于 2025-3-23 09:11:07 | 只看該作者
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