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Titlebook: Cytochrome Oxidase in Neuronal Metabolism and Alzheimer’s Disease; F. Gonzalez-Lima Book 1998 Springer Science+Business Media New York 199

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發(fā)表于 2025-3-21 17:47:19 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Cytochrome Oxidase in Neuronal Metabolism and Alzheimer’s Disease
編輯F. Gonzalez-Lima
視頻videohttp://file.papertrans.cn/243/242607/242607.mp4
圖書封面Titlebook: Cytochrome Oxidase in Neuronal Metabolism and Alzheimer’s Disease;  F. Gonzalez-Lima Book 1998 Springer Science+Business Media New York 199
描述This book is based on an international symposium titled "Cytochrome oxidase in energy metabolism and Alzheimer‘s disease," held as a satellite to the 27th meeting of the Society for Neuroscience, New Orleans, 1997. The symposium was dedicated in honor of Dr. Margaret T. T. Wong-Riley because, in our opinion, the cytochrome oxidase histo- chemical method introduced by Dr. Wong-Riley in 1979 was the most significant break- through to map energy metabolism in the entire brain since the 2-deoxyglucose method introduced by Dr. Louis Sokoloff and colleagues in 1977. Both of these metabolic map- ping techniques have made monumental contributions to brain research by allowing an integral view of brain activity. They have also developed into various specialized tech- niques, including applications to the human brain. One of these new applications, which is described in detail in this book, is the quantitative cytochrome oxidase cytochemical method used to study Alzheimer‘s disease. The objective of this book is to describe the role of cytochrome oxidase in neuronal metabolism and Alzheimer‘s disease. Whether genetic or environmental, the pathogenesis of Alzheimer‘s disease involves a cascad
出版日期Book 1998
關(guān)鍵詞Alzheimer; behavior; gene expression; metabolism; neuroscience
版次1
doihttps://doi.org/10.1007/978-1-4757-9936-1
isbn_softcover978-1-4757-9938-5
isbn_ebook978-1-4757-9936-1
copyrightSpringer Science+Business Media New York 1998
The information of publication is updating

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Cytochrome Oxidase and Neuroanatomical Patternsects in spontaneous or targeted mutant animals. Since C.O. is present in all brain cells, the sensitivity of the histochemical method for showing neuroanatomical patterns may seem paradoxical. In this chapter, I will attempt to explain the remarkable correspondence between C.O. activity and patterns
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Functional Mapping of Learning-Related Metabolic Activity with Quantitative Cytochrome Oxidase Histoerns of functional metabolic activity when the auditory stimulus acquires different behavioral roles through learning. The cytochrome oxidase mapping technique can provide functional images of how the metabolic capacity of intact neural systems change in response to external stimuli.
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Cytochrome Oxidase Inhibition In Alzheimer’s Disease to senile dementia and neurodegeneration in late-onset Alzheimer’s disease in a cascade of multiple intracellular events, initiated primarily by neuronal aerobic energy depletion, mitochondrial formation of reactive oxygen species and disruption of intracellular calcium homeostasis. Quantitative cy
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Behavioral, Electrophysiological, and Biochemical Consequences of Chronic Cytochrome Oxidase Inhibitty that was observed in the hippocampus, but not in frontal or temporal cortex or cerebellum. Further work revealed that the stress hormone, corticosterone, potentiated azide-induced inhibition of C.O. and the resulting cognitive deficits. Thus, manipulation of C.O. activity in rats to mimic biochem
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Cytochrome Oxidasechemia, neurodegenerative changes are still absent but spatial memory remains depressed while the postsynaptic dendritic marker MAP-2 shows loss of immunostaining in the apical dendrites of CA1 neurons (suggesting continued metabolic dysfunction of these neurons). Twelve weeks after brain hypoperfus
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ok, is the quantitative cytochrome oxidase cytochemical method used to study Alzheimer‘s disease. The objective of this book is to describe the role of cytochrome oxidase in neuronal metabolism and Alzheimer‘s disease. Whether genetic or environmental, the pathogenesis of Alzheimer‘s disease involves a cascad978-1-4757-9938-5978-1-4757-9936-1
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