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Titlebook: Cellular Osmolytes; From Chaperoning Pro Laishram Rajendrakumar Singh,Tanveer Ali Dar,Kriti Book 2024Latest edition The Editor(s) (if appli

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發(fā)表于 2025-3-21 16:45:20 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Cellular Osmolytes
副標(biāo)題From Chaperoning Pro
編輯Laishram Rajendrakumar Singh,Tanveer Ali Dar,Kriti
視頻videohttp://file.papertrans.cn/243/242052/242052.mp4
概述Explore the potential of osmolytes as diagnostics, prognostics, or therapeutic agents for human diseases.Discusses the role of osmolytes in various forms of amyloidosis associated with human diseases.
圖書封面Titlebook: Cellular Osmolytes; From Chaperoning Pro Laishram Rajendrakumar Singh,Tanveer Ali Dar,Kriti Book 2024Latest edition The Editor(s) (if appli
描述.The second edition of this book presents the role of osmolytes in human health and diseases. Some of the chapters deal about the possibility of the use of osmolytes as diagnostic biomarkers and potential drug design for neurodegenerative and other human diseases. Other chapters also include reviews on the role of osmolytes in cancer, metastasis, infectious diseases, metabolic disorders, immunological disorders, and tissue regeneration. Importantly, the book also contain recent updates on the role of naturally occurring osmolytes in protein folding pathway, protein stability, and their underlying mechanisms. The book also covers the aspects that osmolytes could promote conformational alterations of transcription factors that favor metastatic behavior. Potential of the osmolytes in the various process of vaccine development, including enhancing the efficacy, production, and purification steps are also succintly described. Towards the end, the book also elucidates the use of specific molecules for the prevention of toxic gain of functions and restoration of function to disease-causing mutant protein. This book is an invaluable asset for the researchers especially working in osmolyte
出版日期Book 2024Latest edition
關(guān)鍵詞Osmolytes; Metabolic diseases; Therapeutic proteins; Disease biomarkers; Protein conformational diseases
版次2
doihttps://doi.org/10.1007/978-981-97-6001-5
isbn_softcover978-981-97-6003-9
isbn_ebook978-981-97-6001-5
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapor
The information of publication is updating

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Role of TMAO on Folding Behavior of Various Proteins Associated with Neurodegeneration,lusions (or protein oligomers) in various regions of the brain. For instance, Aβ accumulation is associated with Alzheimer’s disease. Oligomers of α-synuclein, Htt, and PrP. are associated with Parkinson’s, Huntington’s, and Prion disease respectively. The presence of these oligomers is believed to
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Role of Osmolytes in Cancer,roline, taurine, sarcosine, betaine, sorbitol, glycine, arginine). These molecules are known to protect cells from stressful insults not only by stabilizing macromolecular integrity but also by their involvement in key biological processes e.g. anti-oxidant system, protein quality control system, in
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Diverse Biological Functions of ,-inositol: A Neuro-Metabolite, Osmoprotectant, and Diagnostic Markd. Among different biologically active isomers of the group, .-inositol (MI), is regarded one of the most widespread and versatile metabolite with occurrence in plants, animals, yeasts, and microorganisms. With respect to mammals, MI is particularly abundant in the brain and other organs such as kid
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Potential of Osmolytes as Diagnostic Biomarkers in Various Diseases,cellular homeostasis. Moreover, accumulation of osmolytes in the cells have been implicated in cellular proteostasis through regulating the protein–protein interactions, protein folding, and modulating protein aggregation. Dysregulation/imbalance to the vital osmolytes in the cell may lead to variou
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