Titlebook: Current Understanding and Treatment of Gliomas; Jeffrey Raizer,Andrew Parsa Book 2015 Springer International Publishing Switzerland 2015 C

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Glioma Biology and Molecular Markers,on histologies (oligodendroglioma, mixed oligoastrocytoma, pilocytic astrocytoma). Recent efforts at comprehensive genetic characterization of various primary brain tumor types have identified a number of common alterations and pathways common to multiple tumor types. Common pathways in glioma biolo

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Surgery for Gliomas, to achieve this goal while minimizing the risk of postoperative neurologic deficits, intraoperative brain mapping remains the gold standard. Recent advances in technical aspects of preoperative and intraoperative brain mapping, as well as our understanding of the functional anatomy of the human bra

Rodent

Radiation Therapy of Glioblastoma,have been demonstrated with postoperative radiation therapy (RT) to doses of 5,000–6,000?cGy but dose-escalation attempts beyond 6,000?cGy have resulted in increased toxicity but no additional survival benefit. To improve local control and limit toxicity to normal brain tissue with these infiltratin

CRAFT

Low-Grade Glioma,een 4.7 and 9.8?years. The goal of treatment is to prolong overall survival while maintaining good quality of life (QOL). Recent data favors early surgical resection. EOR is associated with delayed tumor recurrence and improved survival. Additional therapy with chemotherapy or radiation is indicated

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IVORY

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Novel Chemotherapeutic Approaches in Adult High-Grade Gliomas,f the genetic and molecular aberrations that contribute to the aggressive nature of these tumors is continually growing, as is our ability to target such specific traits. Herein, we review the major classes of such targeted therapies, as well as the relevant clinical trial outcomes regarding their e

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Immunotherapy for Malignant Gliomas,omas is an emerging field that promises the possibility of highly specific and less toxic treatment compared to conventional chemotherapy. In addition, immunotherapy has the added benefit of sustained efficacy once immunologic memory is induced. Although there are numerous therapeutic agents that bo

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