Titlebook: Current Topics in Extrapyramidal Disorders; Arvid Carlsson,Kurt Jellinger,Peter Riederer Book 1980 Springer-Verlag/Wien 1980 Birkmayer, Wa

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Blood Platelets as Models for Neurons: Uses and Limitations,ane, (2) inhibitory effects of tricyclic antidepressants and neuroleptics on 5-HT uptake, (3) granular storage of 5-HT and possibly catecholamines, (4) action of drugs interfering with granular and possibly extragranular amine storage and (5) reaction of the 5-HT receptor at the plasma membrane to 5

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Changing Concepts of Nigral Dopamine System Function Within the Basal Ganglia: Relevance to Extrapyn involved in extrapyramidal disorders and has begun to change our concept of how these areas function. One such change has involved our understanding of the role of the dopaminergic system within the basal ganglia. Rather than dopamine being seen primarily as a major influence on striatal Output it

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An Autoradiographic Study of the Striatofugal Fibers in the Monkey,otope in the most medial part of the head and the body of the caudate nucleus fibers were traced along the ventrolateral part of the internal capsule and within the medial part of the comb bündle before penetrating the rostromedial pole of the substantia nigra (SN). Fiber endings were found along th

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Kinetics of L-DOPA Metabolism in the Caudate Nucleus of Cats with Ventrotegmental Lesions,g), and the caudate nucleus from each hemisphere was removed at various time intervals thereafter. In the caudate nucleus contralateral to the VMT lesions, DA levels reached 200 °/o of control values within 15 min, and maintained this elevation for at least 2 hours. DA levels in the caudate nucleus

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Spiroperidol Binding in the Human Caudate Nucleus,sonians and non-parkinsonians at post mortem were investigated. A group of spiroperidol binding sites found in the non-parkinsonians was less strongly expressed or absent in analogous tissue of the parkinsonian. The significance of these findings in relation to Parkinson’s disease and its treatment

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,Contributions of α-Adrenoreceptor Blockade to Extra-pyramidal Effects of Neuroleptic Drugs,d the noradrenaline utilization in the brain of rats. These findings indicate that the first three drugs block central α-adrenoreceptors. The α-methyltyrosine-induced disappearance of dopamine in the corpus striatum and the limbic system was decelerated by prazosin and phenoxybenzamine, was accelera

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patriarch

,Metabolic Alterations in an Animal Model of Huntington’s Disease Using the 14C-Deoxyglucose Method,utoradiographic technique. Rats with kainic acid (KA) lesions of the neostriatum were used as an animal model of HD. KA-injected animals showed reduced utilization of DG in the injected neostriatum as well as in the ipsilateral rostral sulcal cortex, dentate fascia of hippocampus, ventromedial nucle