Titlebook: Cured II - LENT Cancer Survivorship Research And Education; Late Effects on Norm Philip Rubin (Professor Emeritus, Chair Emeritus), Book 20

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Late Toxicity from Hypofractionated Stereotactic Body Radiation,T, the margins for set-up uncertainty can be reduced, allowing greater volume sparing of the surrounding normal tissues. Since SBRT yields a reduced volume of normal tissue exposure, SBRT has been used to increase the fractional dose of radiation (hypofractionation) in an attempt to intensify the do

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0942-5373 portant topics relating to late treatment effects, such as m.Multimodal treatment lies at the heart of the improvement in cancer cure rates. However, the more aggressive the treatment, the more adverse effects in normal tissues can be anticipated. Against this background, a major paradigm shift has

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Book 2008in normal tissues can be anticipated. Against this background, a major paradigm shift has taken place in that there is a new focus on cancer survivorship and quality of life: the life worth saving must be worth living. This volume is based on the CURED II conference held in May 2007, which was atten

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Developments in Hematology and Immunologytastases cause clinical symptoms [., .]. In addition, there is evidence that the overall incidence of brain metastases is increasing because of improved systemic therapy for cancer [.]. Further, the survival rates of children with both primary [.–.], and secondary [.] brain tumors are increasing.

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Platelet Functions and Platelet Transfusionon-induced normal tissue injury has opened up the possibility of biologicallybased interventions to prevent, mitigate or treat these complications. This work has also stimulated efforts to develop strategies to stratify patients according to risk of injury as a means to individualize therapy and improve the therapeutic ratio.