Titlebook: Coronaviruses and Arteriviruses; Luis Enjuanes,Stuart G. Siddell,Willy Spaan Book 1998 The Editor(s) (if applicable) and The Author(s), un

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Characteristics of Remote Sensingolyprotein were used to probe virus infected cells, and detected proteins that correspond to the cleavage sites used by 3CLpro .. These results suggest that MHV 3CLpro cleaves at least 7 sites in the ORF la polyprotein, and that the specificity of 3CLpro for cleavage site dipeptides may be broader than previously predicted.

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Molecular Analysis of the Coronavirus-Receptor Function of Aminopeptidase N further analysis of the mapped amino acid segments by site directed mutagenesis revealed that a short stretch of 8 amino acids in the hAPN protein plays a decisive role in mediating HCV 229E reception.