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Titlebook: Contrast Agents I; Magnetic Resonance I Werner Krause Book 2002 Springer-Verlag Berlin Heidelberg 2002 Filtration.Magnetic Resonance.Magnet

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書(shū)目名稱Contrast Agents I
副標(biāo)題Magnetic Resonance I
編輯Werner Krause
視頻videohttp://file.papertrans.cn/238/237135/237135.mp4
概述This series presents critical reviews of the present position and future trends in modern chemical research.Short and concise reports on chemistry, each written by the world renowned experts.Still val
叢書(shū)名稱Topics in Current Chemistry
圖書(shū)封面Titlebook: Contrast Agents I; Magnetic Resonance I Werner Krause Book 2002 Springer-Verlag Berlin Heidelberg 2002 Filtration.Magnetic Resonance.Magnet
描述Extracellular MRI and X-ray contrast agents are characterized by their phar- cokinetic behaviour.After intravascular injection their plasma-level time curve is characeterized by two phases. The agents are rapidly distributed between plasma and interstitial spaces followed by renal elimination with a terminal half-live of approximatly 1–2 hours. They are excreted via the kidneys in unchanged form by glomerular filtration. Extracellular water-soluble contrast agents to be applied for X-ray imaging were introduced into clinical practice in 1923. Since that time they have proved to be most valuable tools in diagnostics.They contain iodine as the element of choice with a sufficiently high atomic weight difference to organic tissue. As positive contrast agents their attenuation of radiation is higher compared with the attenuation of the surrounding tissue. By this contrast enhancement X-ray diagnostics could be improved dramatically. In 2,4,6-triiodobenzoic acid derivatives iodine is firmly bound. Nowadays diamides of the 2,4,6-triiodo-5-acylamino-isophthalic acid like iopromide (Ultravist, Fig. 1) are used as non-ionic (neutral) X-ray contrast agents in most cases [1].
出版日期Book 2002
關(guān)鍵詞Filtration; Magnetic Resonance; Magnetische Resonanz; Organic Chemistry; Organische Chemie; Physical Chem
版次1
doihttps://doi.org/10.1007/3-540-45733-X
isbn_softcover978-3-642-07596-4
isbn_ebook978-3-540-45733-6Series ISSN 0340-1022 Series E-ISSN 1436-5049
issn_series 0340-1022
copyrightSpringer-Verlag Berlin Heidelberg 2002
The information of publication is updating

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Structures of MRI Contrast Agents in Solution,oordination sphere of the metal ion. Both the Ln. ion and the nitrogen atoms in these complexes may be chiral. Therefore, various isomers may occur for these complexes, which interconvert in aqueous solution. Here studies on the configurations and conformations of Ln. complexes of acyclic and cyclic
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978-3-642-07596-4Springer-Verlag Berlin Heidelberg 2002
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Modellierung der logistischen Zielgr??enproperties and pharmacokinetic behaviour of gadolinium complexes. The synthesis of acyclic and macrocyclic ligands is described, particularly of derivatives of the ligands DTPA and DOTA. Stability, relaxivity and formulations of the gadolinium complexes are issues of special interest as well as thei
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