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Titlebook: Conjugation—Deconjugation Reactions in Drug Metabolism and Toxicity; Frederick C. Kauffman (Director) Book 1994 Springer-Verlag Berlin Hei

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41#
發(fā)表于 2025-3-28 18:03:07 | 只看該作者
Sulfotransferase Enzymestalyzed by those enzymes in tissue preparations. Simultaneously, attempts were made to separate and purify ST enzymes to make it possible to characterize the molecular species that catalyzed specific reactions. Unfortunately, overlap in substrate specificities of these enzymes has led to confusion w
42#
發(fā)表于 2025-3-28 20:21:30 | 只看該作者
43#
發(fā)表于 2025-3-29 02:09:35 | 只看該作者
Microsomal Amidases and Carboxylesterases they hydrolyze the esters of fatty acids, such as palmitoyl-Lcarnitine, 1-palmitoyl glycerol, and oleoyl cholesterol, the physiological role of amidases/carboxylesterases is not yet clear (M. et al. 1988).
44#
發(fā)表于 2025-3-29 05:48:35 | 只看該作者
-, ,- and ,-Methyltransferasesy all these enzymes, i.e., .-adenosyl-.-methionine (AdoMet). The .-methylation (T. and C. 1990; B. et al. 1990; C. 1993; K. et al. 1992), .-methylation (A. and J. 1990), and S-methylation (S. and B. 1990; H. 1993) reactions have been discussed in recent comprehensive reviews.
45#
發(fā)表于 2025-3-29 07:49:56 | 只看該作者
46#
發(fā)表于 2025-3-29 15:15:14 | 只看該作者
Regulation of Drug Conjugate Processing by Hepatocellular Transport Systems the basolateral domain to be excreted in the urine? Is this determined by the presence and substrate specificity of transporters in each membrane domain? How are drug conjugates which are formed in other tissues, such as the intestine, taken up by the liver? Recent advances have provided answers to
47#
發(fā)表于 2025-3-29 18:57:08 | 只看該作者
48#
發(fā)表于 2025-3-29 21:27:57 | 只看該作者
49#
發(fā)表于 2025-3-30 00:08:19 | 只看該作者
50#
發(fā)表于 2025-3-30 05:22:36 | 只看該作者
Die Kapitalflussrechnung nach IFRS961; J. 1965; E. and W. 1964), the term “inactivator” was supplanted by “acetylator.” Since then, the two genetically distinct major phenotypes have usually been referred to as rapid and slow acetylators.
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