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Titlebook: Computer Simulations of Protein Structures and Interactions; S. Fraga,J. M. R. Parker,J. M. Pocock Book 1995 Springer-Verlag Berlin Heidel

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書(shū)目名稱(chēng)Computer Simulations of Protein Structures and Interactions
編輯S. Fraga,J. M. R. Parker,J. M. Pocock
視頻videohttp://file.papertrans.cn/234/233929/233929.mp4
叢書(shū)名稱(chēng)Lecture Notes in Chemistry
圖書(shū)封面Titlebook: Computer Simulations of Protein Structures and Interactions;  S. Fraga,J. M. R. Parker,J. M. Pocock Book 1995 Springer-Verlag Berlin Heidel
描述Protein engineering endeavors to design new peptides and proteins or to change the structural and/or functional characteristics of existing ones for specific purposes, opening the way for the development of new drugs. This work develops in a comprehensive way the theoretical formulation for the methods used in computer-assisted modeling and predictions, starting from the basic concepts and proceeding to the more sophisticated methods, such as Monte Carlo and molecular dynamics. An evaluation of the approximations inherent to the simulations will allow the reader to obtain a perspective of the possible deficiencies and difficulties and approach the task with realistic expectations. Examples from the authors laboratories, as well as from the literature provide useful information.
出版日期Book 1995
關(guān)鍵詞Interactions; Interaktion; Modeling; Modell-Bildung; Peptide; Protein; Proteine; Structures; Strukturen; data
版次1
doihttps://doi.org/10.1007/978-3-642-51499-9
isbn_softcover978-3-540-60133-3
isbn_ebook978-3-642-51499-9Series ISSN 0342-4901 Series E-ISSN 2192-6603
issn_series 0342-4901
copyrightSpringer-Verlag Berlin Heidelberg 1995
The information of publication is updating

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Book 1995te Carlo and molecular dynamics. An evaluation of the approximations inherent to the simulations will allow the reader to obtain a perspective of the possible deficiencies and difficulties and approach the task with realistic expectations. Examples from the authors laboratories, as well as from the literature provide useful information.
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https://doi.org/10.1057/9780230375857ases is the existence of molecular associations, which are the result of the molecular recognition process (Jaenicke 1987). The study of these interactions, already of interest ., has the added significance of extremely important practical applications, such as the rational design of vaccines and drugs, as discussed in Chapter 12.
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The Conservative Counter-revolution, (identical or not). We must realize, of course, that this statement, though correct in principle, does not reflect the reality, considering the many practical difficulties to be encountered in the implementation of those computational schemes.
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,Between Balfour and Baldwin 1911–1923,consequently, the computing time required for the simulations. These considerations are not independent of each other and the final approach adopted may imply the inclusion of additional approximations, as explained below.
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