Titlebook: Computational Neurology and Psychiatry; Péter érdi,Basabdatta Sen Bhattacharya,Amy L. Coch Book 2017 Springer International Publishing AG

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https://doi.org/10.1007/978-3-319-49959-8Neurocomputational Models; Brain Decision-Making; Models of Mood; Modeling Neural Circuits; Brain Connec

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978-3-319-84284-4Springer International Publishing AG 2017

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Computational Neurology and Psychiatry978-3-319-49959-8Series ISSN 2193-9349 Series E-ISSN 2193-9357

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Introduction,reader is introduced to neuroscience and the strategic importance of research on the brain in the present day and age. A brief historical perspective on the underlying mathematical models along with an overview of advancement in the field of computational neurology and psychiatry are discussed. The

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,Extracellular Potassium and Focal Seizures—Insight from In Silico Study,work behaviour. In particular, we show that in the model, strong discharge of inhibitory interneurons may result in long lasting accumulation of extracellular K., which sustains depolarization of principal cells and causes their pathological discharges. This effect is not present in a reduced model

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Time Series and Interactions: Data Processing in Epilepsy Research,methods for analyzing continuous signals, methods that include time-frequency analysis and entropy calculations. We finish this chapter with methods for determining causal interactions among signals and how these latter methods can be used to locate the epileptic foci.

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Mathematical Models of Neuromodulation and Implications for Neurology and Psychiatry,enetic polymorphisms and we explain why the brain serotonin concentration depends on diet but the dopamine concentration does not. We discuss the traditional hypotheses about the mechanism of action of selective sserotonin reuptake inhibitors (SSRIs), and introduce a new hypothesis about the mechani

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