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Titlebook: Computational Methods in Systems Biology; 11th International C Ashutosh Gupta,Thomas A. Henzinger Conference proceedings 2013 Springer-Verl

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On the Verification and Correction of Large-Scale Kinetic Models in Systems Biologyted on biochemical models taken from the Biomodels database. In particular, a set of 11 kinetic models related with . are checked, finding two with deficiencies. Correcting actions for these models are proposed.
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發(fā)表于 2025-3-29 20:27:04 | 只看該作者
Bojan Lalic,Vidosav Majstorovic,David Romeroade of yeast pheromone response signaling. Results demonstrate that the molecules of the MAPK cascade co-localize along scaffold molecules, while the scaffold binds to a plasma membrane bound upstream component, localizing the whole signaling complex to the plasma membrane. Especially we show, how r
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發(fā)表于 2025-3-30 01:53:17 | 只看該作者
Production Internet - Functional Perspectivector (GDNF), which is expressed in the mesenchyme and induces outgrowth of ureteric branches. Considering that the Turing model represents the interaction between the GDNF and its receptor RET very well and that the model reproduces the relevant expression patterns in developing wildtype and mutant
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發(fā)表于 2025-3-30 08:02:48 | 只看該作者
https://doi.org/10.1007/978-3-319-66923-6ocedures. We have evaluated our method on two large pathway models, namely, the segmentation clock network and the thrombin-dependent MLC phosphorylation pathway. The results show that our method scales well and yields good parameter estimates that are robust. Our sensitivity analysis framework lead
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