Titlebook: Computational Methods for Protein Structure Prediction and Modeling; Volume 2: Structure Ying Xu,Dong Xu,Jie Liang Book 2007 Springer-Verl

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, Protein Structure Prediction,nation of the function of a gene of interest, as long as there is an existing sequenced gene with similar sequence and of known function. This has spurred structural genomic initiatives with the goal of determining as many protein folds as possible (.; .; .; .). The purpose of this is twofold: First

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Structure Prediction of Membrane Proteins,0% of the proteome (.; .; .). They are essential mediators of material and information transfer across cell membranes. Their functions include active and passive transport of molecules into and out of cells and organelles; transduction of energy among various forms (light, electrical, and chemical e

intelligible

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Structure-Based Drug Design,e to minimize damage to the healthy parts. The quest of drug discovery is to identify the causes of the phenotype of the disease, and to interfere with the abnormal gene or gene product in such a manner that the disease is cured. Selectivity for just the aberrant gene products remains the critical p

ABHOR

Protein Structure Prediction as a Systems Problem,is complexity, a large number of computational methods have been developed, as discussed in the previous chapters of this book. When the protein structure prediction problem was first formulated, it was envisioned that one could computationally predict any protein structure through solving a minimiz

ABHOR

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