Titlebook: Combined Effects of Drugs and Toxic Agents; Modern Evaluation in Gerald P?ch Book 1993 Springer-Verlag/Wien 1993 biochemistry.chemotherapy.

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Principle considerations of drug actions and interactions,er one is concerned with combined effects, the more one realizes that almost everyone has their own opinion. Probably the great majority of researchers shares the opinion that the topic of combined effects is a continuing problem, especially with “synergistic” agents in combination.

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Compact Textbooks in Mathematicsnd Shipman 1990, Sühnel 1992), in principle invented by Loewe (1953), or two-dimensionally by isobolograms, DRCs or histograms. This chapter deals with a new graph, termed combined-effect graph, and a graphical comparison of observed with calculated independent effects. Also, reference is given to the Yonetani-Theorell plot.

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Vector Bundles and Projective Modules,ice. The reader is expected to understand the current dilemma of disagreement in the analysis and interpretation of effects in combination after a careful and unbiased study of this book. Possibly a few points still remain unclear.

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