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Titlebook: Combination Vaccines; Development, Clinica Ronald W. Ellis (Vice-President, General Manager) Book 1999 Springer Science+Business Media New

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書(shū)目名稱Combination Vaccines
副標(biāo)題Development, Clinica
編輯Ronald W. Ellis (Vice-President, General Manager)
視頻videohttp://file.papertrans.cn/230/229864/229864.mp4
圖書(shū)封面Titlebook: Combination Vaccines; Development, Clinica Ronald W. Ellis (Vice-President, General Manager) Book 1999 Springer Science+Business Media New
描述A diverse team of leading experts comprehensively review the complex biology of a wide variety of vaccine combinations, as well as the technical, clinical, and regulatory aspects of their development. Topics covered range from the use of immunological correlates of efficacy, rather than efficacy per se, for the evaluation and licensure of vaccine combinations, to preserving a stable immunogenic mixture in appropriate containers according to accepted regulatory standards. Discussed in detail are the trivalent influenza vaccine, the pneumococcal polysaccharide vaccine, the MMR vaccine, the DTP vaccine and its combinations, and the quadrivalent rotavirus vaccine, all of which serve as models for the development of future combinations. Combination Vaccines: Development, Clinical Research, and Approval illuminates all the scientific, clinical, regulatory, and health care issues involved in the research, development, and human use of combination vaccines...... ..
出版日期Book 1999
關(guān)鍵詞clinical research; diseases; infectious disease; research; vaccine
版次1
doihttps://doi.org/10.1007/978-1-59259-265-4
isbn_softcover978-1-4757-4802-4
isbn_ebook978-1-59259-265-4
copyrightSpringer Science+Business Media New York 1999
The information of publication is updating

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Pediatric Combination Vaccines,ace the challenge of replacing existing, proven vaccines. Therefore, they must fulfill all of the criteria for new vaccines in terms of safety and efficacy and in addition must be shown to be as good as the components given separately.
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Immunological Correlates for Efficacy of Combination Vaccines,ase 3 clinical trial with disease as an endpoint. The group receiving the vaccine is compared to a control group (e.g., receiving placebo, historical control, case control) in order to calculate the level of efficacy.
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Influenza Vaccines,0,000 people after an acute epidemic .. Additionally, in terms of physician and hospital expenses and time away from work, the dollar cost to the United States economy is immense. The Surgeon General of the United States Public Health Service estimated that at least 43 million Americans are at risk
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Rotavirus Vaccines,genetically reassorting one animal rotavirus strain (i.e., simian or bovine) with each of several human rotavirus strains. The resultant reassortant strains retain the attenuated virulence characteristics of the animal strains and express one of the genes that encode the proteins that determine huma
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