Titlebook: Clostridium difficile; Klaus Aktories,Tracy D. Wilkins (Director of Biote Book 2000 The Editor(s) (if applicable) and The Author(s), under

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Georg Juckel,F. Schlagenhauf,A. Heinzoice has been toward greater use of metronidazolc rather than vancomycin because of increasing concern about vancomycin resistance in organisms such as the enterococcus (HICPAC 1995). However, this should not be interpreted to mean that improvements in therapy are not needed. There continue to be ma

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Microbiology, Epidemiology and Diagnosis of , Infection,s. Although they postulated that toxins from certain strains, when liberated in the infant gut, might play a role in conditions such as the formation of occult blood and febrile convulsions of the newborn. it was not until 1969 that the first real clue to the pathogenic potential of this organism to

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Large Clostridial Cytotoxins as Tools in Cell Biology,V. E.-S. et al. 1996; B.: et al. 1998). This designation came from their molecular mass of about 300kDa and their obvious cytotoxic activity to induce disaggregation of the actin cytoskeleton. Despite their comparable toxic activities towards cultured cell lines, the toxins are produced by strains w