Titlebook: Chronic Leukemias and Lymphomas; Biology, Pathophysio Gary J. Schiller Book 2003 Springer Science+Business Media New York 2003 Staging.biol

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Hairy Cell Leukemia,he median age is 52 yr at presentation, with a 4:1 male predominance. The disease is rare in Asian or African Americans, and has a higher incidence in Ashkenazi Jews, and occasional familial cases have been described .,..

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Prolymphocytic Leukemias,% of the cases are of B-cell phenotype. Definitional problems exist regarding specificity of diagnosis for these unusual leukemias. The recent World Health Organization (WHO) classification recognizes the existence of these entities and attempts to delineate specific diagnostic criteria.

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,Sézary Syndrome, . wrote of a patient who presented with complaints of intense pruritus, who was found to have erythroderma, lymphadenopathy, and abnormal “monster” hyper-convoluted mononuclear cells circulating in the peripheral blood. Twenty-three years later, the Sézary syndrome was recognized in the American medical literature by Taswell and Winkelmann ..

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在前面

Aggressive Large-Cell Lymphomas,pproximately 30%, 6%, and 2% of newly diagnosed non-Hodgkin’ s lymphomas, respectively .. Although they are clearly different diseases biologically, these illnesses share a number of clinical characteristics. The epidemiology, pathogenesis/biology, diagnosis, and treatment of these disorders is discussed in this chapter.

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Gary J. SchillerIncludes supplementary material:

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Current Clinical Oncologyhttp://image.papertrans.cn/c/image/226387.jpg

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Reflections on a United Nations‘ Career150 years ago. In the following years, physicians have recognized the heterogeneous spectrum of leukemia. They also developed a fuller understanding of the clinical features, natural history, and morphology of leukemia. The classification of leukemia into its various subtypes became possible in the mid-twentieth century.

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You Must Be Mad: UN Headquarters,linical features are the sequelae of bone marrow failure and the compressive syndromes that result from gross enlargement of lymphoid organs. In addition, CLL is associated with humoral and cell-mediated immunodeficiencies as well as a greatly enhanced risk of autoimmune cytopenias—particularly autoimmune hemolytic anemia (AIHA).