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Titlebook: Chromatin Regulation of Early Embryonic Lineage Specification; Jason Knott,Keith Latham Book 2018 The Editor(s) (if applicable) and The Au

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發(fā)表于 2025-3-21 19:25:25 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Chromatin Regulation of Early Embryonic Lineage Specification
編輯Jason Knott,Keith Latham
視頻videohttp://file.papertrans.cn/227/226302/226302.mp4
概述Examines the roles of early acting chromatin regulators in ICM and TE formation.Explores the role of RHOA subfamily of small GTPases and RHO-associated coiled-coil kinases.Provides an overview on the
叢書名稱Advances in Anatomy, Embryology and Cell Biology
圖書封面Titlebook: Chromatin Regulation of Early Embryonic Lineage Specification;  Jason Knott,Keith Latham Book 2018 The Editor(s) (if applicable) and The Au
描述.Five leaders in the field of mammalian preimplantation embryo development provide their own perspectives on key molecular and cellular processes that mediate lineage formation during the first week of life. The first cell-fate decision involves the formation of the pluripotent inner cell mass (ICM) and extraembryonic trophectoderm (TE). The second cell-fate choice encompasses the transformation of ICM into extraembryonic primitive endoderm (PE) and pluripotent epiblast. The processes, which occur during the period of preimplantation development, serve as the foundation for subsequent developmental events such as implantation, placentation, and gastrulation. The mechanisms that regulate them are complex and involve many different factors operating spatially and temporally over several days to modulate embryonic chromatin structure, impose cellular polarity, and direct distinct gene expression programs in the first cell lineages.?.
出版日期Book 2018
關(guān)鍵詞extraembryonic primitive endoderm; pluripotent epiblast; embryonic chromatin structure; CHD1; CHD4; H3R26
版次1
doihttps://doi.org/10.1007/978-3-319-63187-5
isbn_softcover978-3-319-63186-8
isbn_ebook978-3-319-63187-5Series ISSN 0301-5556 Series E-ISSN 2192-7065
issn_series 0301-5556
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl
The information of publication is updating

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ROCK and RHO Playlist for Preimplantation Development: Streaming to HIPPO Pathway and Apicobasal Poptional co-activators YAP/TAZ, the downstream effectors of HIPPO signaling. Nuclear localization of YAP/TAZ depends on the formation of apicobasal polarity in outside cells, which requires activities of RHO/ROCK. We propose models of how RHO/ROCK regulate lineage specification and lay out challenges
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0301-5556 ulate them are complex and involve many different factors operating spatially and temporally over several days to modulate embryonic chromatin structure, impose cellular polarity, and direct distinct gene expression programs in the first cell lineages.?.978-3-319-63186-8978-3-319-63187-5Series ISSN 0301-5556 Series E-ISSN 2192-7065
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發(fā)表于 2025-3-22 17:58:12 | 只看該作者
Reconstructive Microvascular Surgeryremodellers play essential roles in the successful completion of preimplantation development in mammals and describe recent efforts to understand the molecular mechanisms through which chromatin remodellers facilitate the successful completion of the first cell fate decisions in mammalian embryogene
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Reconstructive Microvascular Surgeryression, elucidation of the underlying mechanisms remains challenging. In this chapter, we propose that the chromatin remodeling factor CHD1, together with epigenetic factors, is involved in a subset of gene expression networks involved in processes spanning from zygotic genome activation to cell li
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發(fā)表于 2025-3-23 04:31:07 | 只看該作者
Reconstructive Microvascular Surgeryptional co-activators YAP/TAZ, the downstream effectors of HIPPO signaling. Nuclear localization of YAP/TAZ depends on the formation of apicobasal polarity in outside cells, which requires activities of RHO/ROCK. We propose models of how RHO/ROCK regulate lineage specification and lay out challenges
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