Titlebook: Cholesterol Modulation of Protein Function; Sterol Specificity a Avia Rosenhouse-Dantsker,Anna N. Bukiya Book 2019 The Editor(s) (if applic

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Problemstellung und Zielsetzung,rior) which is located in the lipid headgroup region of the membrane, between the linkage of the hydrocarbon chains to the phospholipid glycerol backbone and the adjacent aqueous solution. At its physiological level in animal plasma membranes (up to 50?mol%), cholesterol makes a significant contribu

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Rechnerunterstützte Arbeitsplatzgestaltungs spectrometry imaging technology and applications focused on mapping cholesterol. Secondary ion mass spectrometry (SIMS), matrix-assisted laser desorption/ionization (MALDI), and desorption electrospray (DESI) modes are described. These MSI technologies range in spatial resolution, and therefore di

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Rechnerunterstützte Arbeitsplatzgestaltungand cholesterol-derived molecular imaging are provided as well as imaging results from membrane dynamics, and genetic and drug treatment models. This emerging application of MSI for mapping cholesterol in biological specimens provides a new means to gain a deeper understanding of cholesterol distribution, and thereby insights into function.

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Mass Spectrometry Imaging of Cholesteroland cholesterol-derived molecular imaging are provided as well as imaging results from membrane dynamics, and genetic and drug treatment models. This emerging application of MSI for mapping cholesterol in biological specimens provides a new means to gain a deeper understanding of cholesterol distribution, and thereby insights into function.

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A Critical Analysis of Molecular Mechanisms Underlying Membrane Cholesterol Sensitivity of GPCRss mediate a wide range of physiological processes and have emerged as major targets for the development of novel drug candidates in all clinical areas. Since GPCRs are integral membrane proteins, regulation of their organization, dynamics, and function by membrane lipids, in particular membrane chol

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