Titlebook: Cholera Outbreaks; G. Balakrish Nair,Yoshifumi Takeda Book 2014 The Editor(s) (if applicable) and The Author(s), under exclusive license t

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Circulation and Transmission of Clones of , During Cholera Outbreaks,s the population of the pathogen expands, many novel mutations may be found increasing the amount of genetic variation, a phenomenon known as a founder flush. In Haiti, after the initial invasion and expansion of . in 2010, a second outbreak occurred in the winter of 2011–2012 driven by natural sele

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Genomic Science in Understanding Cholera Outbreaks and Evolution of , as a Human Pathogen,osely related, regardless of region of origin. Non-O1 clinical or environmental strains may also possess some virulence islands, but phylogenic analysis of the core genome suggests they are more diverse and distantly related than those isolated during epidemics. Like Haiti, genomic studies that exam

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When, How, and Where can Oral Cholera Vaccines be Used to Interrupt Cholera Outbreaks?,yed, as well as effective and rapid coordination of processes and logistics used to make decisions on deployment and delivery of the vaccine to the population in need. Despite not having data on all the questions of relevance as to how to use OCVs to control cholera outbreaks in different settings,

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0070-217X ow this information can be used to control cholera outbreaks. The book closes with an analysis of the potential use of killed oralcholera vaccines to stop the spread of cholera outbreaks..978-3-662-52271-4978-3-642-55404-9Series ISSN 0070-217X Series E-ISSN 2196-9965

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Cholera Outbreaks in South-East Asia,EARO classification of the member countries of the region. Therefore, the chapter attempts to provide a comprehensive yet precise outline of the major cholera outbreaks that have occurred in the region over the years.

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The Cholera Outbreak in Haiti: Where and How did it begin?,read of cholera in Haiti and worldwide. In this chapter, we discuss both the results of the Independent Panel’s investigation and the context the report sat within; including background information, responses to the report’s release, additional research subsequent to our report, and the public health implications of the Haiti cholera epidemic.

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